Goudot Mathilde, Groh Matthieu, Salah Sawsen, Monnet Dominique, Blanche Philippe, Brézin Antoine P
a Department of Ophthalmology , Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Université Paris Descartes , Paris , France.
b Department of Internal Medicine , National Referral Center for Rare Autoimmune and Systemic Diseases, Hôpital Cochin, Assistance Publique Hôpitaux de Paris, Université Paris Descartes , Paris , France.
Ocul Immunol Inflamm. 2017 Apr;25(2):196-201. doi: 10.1080/09273948.2017.1291841. Epub 2017 Mar 10.
This study aimed at reporting lymphocytic meningitis in patients diagnosed with sympathetic ophthalmia (SO).
In this single-center retrospective observational case series, we reviewed cases diagnosed with SO. We analyzed the patients' inciting injuries, the characteristics of uveitis and the cerebrospinal fluid (CSF) analyses.
Nine patients were diagnosed with SO and CSF analyses were available in all cases. Four cases had lymphocytic pleocytosis, 3 of which showed marked CSF inflammation with more than 300 lymphocytes/mm. The inciting event in these 3 patients was a globe perforation injury, whereas 4 patients without meningitis had SO following a surgical intervention.
In this case series of patients with SO, lymphocytic meningitis was a common finding. The prevalence of meningitis in patients with SO and its value for the diagnosis of the disease needs to be further studied.
本研究旨在报告被诊断为交感性眼炎（SO）的患者中的淋巴细胞性脑膜炎。
在这个单中心回顾性观察病例系列中，我们回顾了被诊断为SO的病例。我们分析了患者的诱发损伤、葡萄膜炎特征和脑脊液（CSF）分析结果。
9例患者被诊断为SO，所有病例均进行了CSF分析。4例出现淋巴细胞增多，其中3例显示CSF明显炎症，淋巴细胞超过300/mm。这3例患者的诱发事件为眼球穿孔伤，而4例无脑膜炎的患者在手术干预后发生了SO。
在这个SO患者病例系列中，淋巴细胞性脑膜炎是一个常见发现。SO患者中脑膜炎的患病率及其对该疾病诊断的价值有待进一步研究。
