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失去一只脚与失去一美元;糖尿病足并发症成本研究的系统评价

Losing a foot versus losing a dollar; a systematic review of cost studies in diabetic foot complications.

作者信息

Petrakis Ioannis, Kyriopoulos Ilias J, Ginis Alexandros, Athanasakis Kostas

机构信息

a National School of Public Health , Health Economics Department , Athens , Greece.

b Medical Department , Takeda Hellas , Marousi , Greece.

出版信息

Expert Rev Pharmacoecon Outcomes Res. 2017 Apr;17(2):165-180. doi: 10.1080/14737167.2017.1305891. Epub 2017 Mar 17.

DOI:10.1080/14737167.2017.1305891
PMID:28283002
Abstract

Diabetes mellitus is a chronic disease with high prevalence worldwide and a range of serious related complications. Amongst them, diabetic foot is one of the most disabling, posing a substantial health and economic burden on patients and healthcare systems. Areas covered: According to projections, the expected lower limb morbidity is about to increase - in this light the present review aimed at identifying cost-of-illness studies on the management and treatment of conditions related to the diabetic foot, in an aim to provide a body of evidence for an increasing health care burden. Expert commentary: Recent literature review surfaced a plethora of cost studies. Despite heterogeneity of foot complications and geographic variations, the search methodology revealed substantial costs and further healthcare burden for people with diabetes. Amputations due to suboptimally treated foot infections contribute to the already high rates of hospitalizations and readmissions. The cost of amputation ranges between $35,000 and $45,000 in the developed countries, however it largely depends on the amputation type. Moreover, the findings suggest that the cost of amputation in the US is generally higher compared to the cost in European countries. The cost of amputation in developing countries is substantially lower, as it approximates $5,000.

摘要

糖尿病是一种在全球范围内具有高患病率且伴有一系列严重相关并发症的慢性疾病。其中,糖尿病足是最具致残性的病症之一,给患者和医疗系统带来了巨大的健康和经济负担。涵盖领域:据预测,下肢发病率预计将会上升——鉴于此,本综述旨在识别有关糖尿病足相关病症管理和治疗的疾病成本研究,以便为日益增加的医疗负担提供证据。专家评论:近期的文献综述涌现出大量成本研究。尽管足部并发症存在异质性且地域有所不同,但检索方法显示糖尿病患者存在巨大成本以及进一步的医疗负担。因足部感染治疗不充分导致的截肢增加了本就居高不下的住院率和再入院率。在发达国家,截肢成本在35,000美元至45,000美元之间,不过这在很大程度上取决于截肢类型。此外,研究结果表明,美国的截肢成本总体上高于欧洲国家。发展中国家的截肢成本则大幅降低,约为5,000美元。

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