Villarreal-Garza Cynthia, Martinez-Cannon Bertha Alejandra, Platas Alejandra, Mohar Alejandro, Partridge Ann H, Gil-Moran Arnoldo, Fonseca Alan, Vega Yoatzin, Bargallo-Rocha Enrique, Cardona-Huerta Servando, Lopez-Aguirre Yadira Estefany, Barragan-Carrillo Regina, Castro-Sanchez Andrea
Departamento de Investigacion y de Tumores Mamarios, Instituto Nacional de Cancerologia, Mexico City, Mexico; Centro de Cancer de Mama, Tecnologico de Monterrey, Monterrey, N.L., Mexico; Joven y Fuerte: Programa para la Atencion e Investigacion de Mujeres Jovenes con Cancer de Mama, Mexico City, Mexico.
Centro de Cancer de Mama, Tecnologico de Monterrey, Monterrey, N.L., Mexico; Joven y Fuerte: Programa para la Atencion e Investigacion de Mujeres Jovenes con Cancer de Mama, Mexico City, Mexico.
Breast. 2017 Jun;33:71-75. doi: 10.1016/j.breast.2017.02.010. Epub 2017 Mar 8.
Young women represent a high proportion of the total number of breast cancer (BC) patients in Mexico; however, no previous studies addressing their attitudes regarding the risk of chemotherapy-induced infertility and its contributing factors are available. The aim of this study was to evaluate the concerns of young women with BC towards the risk of infertility in two referral centers in Mexico with access to public health services.
A cross-sectional study including women with newly or previously detected BC aged 40 years or younger at diagnosis was conducted. Variables regarding concerns about fertility were collected from an adapted version of the Fertility Issues Survey.
134 consecutive eligible women responded to the in-person paper survey. 55% were partnered, 35.1% had no children, and 48% reported willingness to have children prior to BC diagnosis. Only 3% of patients considered to be able to afford extra expenses. At diagnosis, 44% of women expressed some level of concern about infertility risk. The only factor significantly associated with fertility concern was the desire of having children prior to diagnosis (OR 11.83, p = 0.006). Only 30.6% patients recalled having received information regarding infertility risk from their physicians.
A minority of young women with breast cancer in Mexico is informed about the risk of BC treatment-induced infertility, despite substantial interest. Informing all patients about infertility risk and available options for fertility preservation should be an essential aspect of the supportive care of young women with BC, even in low-middle income countries such as Mexico.
在墨西哥，年轻女性在乳腺癌（BC）患者总数中占比很高；然而，此前尚无针对她们对化疗导致不孕风险及其影响因素态度的研究。本研究的目的是评估墨西哥两个可获得公共卫生服务的转诊中心中年轻乳腺癌女性对不孕风险的担忧。
开展一项横断面研究，纳入诊断时年龄在40岁及以下的新诊断或既往诊断为乳腺癌的女性。关于生育问题的变量从一份改编后的《生育问题调查问卷》中收集。
134名符合条件的女性连续参与了纸质问卷调查。55%的女性处于恋爱关系，35.1%没有孩子，48%的女性报告在乳腺癌诊断前有生育意愿。只有3%的患者认为自己能够承担额外费用。在诊断时，44%的女性对不孕风险表达了一定程度的担忧。与生育担忧显著相关的唯一因素是在诊断前有生育意愿（比值比11.83，p = 0.006）。只有30.6%的患者回忆起从医生那里得到过关于不孕风险的信息。
在墨西哥，尽管有很大兴趣，但少数年轻乳腺癌女性了解乳腺癌治疗导致不孕的风险。告知所有患者不孕风险及可用的生育力保存选择，应成为年轻乳腺癌女性支持性护理的一个重要方面，即便在像墨西哥这样的中低收入国家。
