女性慢性肾脏病患者的生殖问题及相关因素：一项多中心横断面研究。
Reproductive concerns and associated factors among female chronic kidney diseases patients: a Multi-Center Cross-Sectional Study.
机构信息
Department of Nephrology, West China Hospital, Sichuan University/ West China School of Nursing, Sichuan University, Chengdu, Sichuan, China.
Department of Biostatistics, University of Michigan, Ann Arbor, MI, USA.
出版信息
Nurs Open. 2021 Sep;8(5):2743-2749. doi: 10.1002/nop2.850. Epub 2021 Mar 10.
AIM
The study aimed to investigate the current status of reproductive concerns and explore the associated factors among young female chronic kidney disease (CKD) patients.
DESIGN
A multi-center cross-sectional study was designed.
METHODS
The study was conducted in six representative tertiary hospitals across southwest China. A total of 295 female Chronic kidney disease patients between 18-45 years of age completed a 20 min, web-based survey, which included demographics and disease-related information questionnaire, Reproductive Concerns Scale, Generalized Anxiety Disorder 7 (GAD-7) instrument and Patient Health Questionnaire 9 (PHQ-9) instrument.
RESULT
The survey total collected 270 valid questionnaires. The mean reproductive concern score was 54.39 ± 10.90 (out of a maximum of 90), with the mean scores for sub-scales ranging from 7.80 ± 1.69 to 10.44 ± 1.85. Multiple regression analysis showed that those with higher reproductive concerns were more likely to have pregnancy intentions, to be in Chronic kidney disease stages 1-3, and to have a higher GAD-7 score. This study offered further evidence of the need for improved education and emotional support surrounding reproductive concerns among young Chinese women with Chronic kidney disease.
目的
本研究旨在调查年轻女性慢性肾脏病（CKD）患者的生殖关注现状，并探讨其相关因素。
设计
采用多中心横断面研究设计。
方法
本研究在西南地区的六家有代表性的三级医院进行。共有 295 名年龄在 18-45 岁之间的女性慢性肾脏病患者完成了一项 20 分钟的网络调查，内容包括人口统计学和疾病相关信息问卷、生殖关注量表、广泛性焦虑障碍 7 项量表（GAD-7）和患者健康问卷 9 项量表（PHQ-9）。
结果
共收集了 270 份有效问卷。生殖关注总评分的平均值为 54.39±10.90（满分 90 分），各分量表的平均得分范围为 7.80±1.69 至 10.44±1.85。多因素回归分析显示，生殖关注程度较高的患者更有可能有生育意愿、处于慢性肾脏病 1-3 期、GAD-7 评分较高。本研究进一步证明，需要加强对中国年轻女性慢性肾脏病患者生殖关注问题的教育和情感支持。
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