Slootweg P J, Müller H
Department of Oral Pathology, University of Utrecht, the Netherlands.
J Craniomaxillofac Surg. 1987 Dec;15(6):359-64. doi: 10.1016/s1010-5182(87)80083-5.
Fifteen cases of a recently-described type of adenocarcinoma of salivary gland tissue are reviewed. Lesions are variously designated polymorphous low-grade adenocarcinoma, low-grade papillary adenocarcinoma, terminal duct carcinoma and lobular carcinoma. Tumours were divided into those with papillary structures (8 cases) and those without (7 cases), respectively low-grade papillary adenocarcinoma (LGPA) and terminal duct adenocarcinoma (TDA). Mean age of TDA-cases was 59.1 years; of the LGPA-cases 64.2-years. TDA's occurred anywhere in the mouth whereas LGPA's occurred in all but two cases in the hard palate. Three of the TDA-patients exhibited recurrent tumours as did 1 of the LGPA-patients. Metastatic disease was shown by 2 of the LGPA-patients. It is concluded that TDA and LGPA show sufficient difference in histopathological and clinical aspects to justify separating them. Both lesions are equally prone to local recurrence but it is the papillary type that can give origin to local and distant metastatic disease. The relation between LGPA and TDA on the one hand and adenoid cystic carcinoma on the other is discussed, leading to the conclusion that although there are some similarities, differences prevail.
本文回顾了15例最近描述的涎腺组织腺癌病例。这些病变有多种命名，包括多形性低度腺癌、低度乳头状腺癌、终末导管癌和小叶癌。肿瘤被分为有乳头状结构的（8例）和无乳头状结构的（7例），分别为低度乳头状腺癌（LGPA）和终末导管腺癌（TDA）。TDA病例的平均年龄为59.1岁；LGPA病例为64.2岁。TDA可发生于口腔的任何部位，而LGPA除两例外在硬腭均有发生。3例TDA患者出现复发肿瘤，LGPA患者中有1例复发。2例LGPA患者出现转移。结论是TDA和LGPA在组织病理学和临床方面表现出足够的差异，足以将它们区分开来。两种病变局部复发的倾向相同，但乳头状类型可导致局部和远处转移。文中还讨论了LGPA和TDA与腺样囊性癌之间的关系，得出的结论是，尽管存在一些相似之处，但差异更为显著。
