耳垂褶皱（弗兰克氏征）的古病理学：来自文艺复兴时期艺术的新见解。
Palaeopathology of the earlobe crease (Frank's sign): New insights from Renaissance art.
作者信息
Galassi Francesco M, Borghi Claudio, Ballestriero Roberta, Habicht Michael E, Henneberg Maciej, Rühli Frank J
机构信息
Institute of Evolutionary Medicine, University of Zurich, Winterthurerstrasse 190, 8057 Zurich, Switzerland.
Medical and Surgical Sciences Department, University of Bologna, Via Massarenti 9, Bologna, Italy.
出版信息
Int J Cardiol. 2017 Jun 1;236:82-84. doi: 10.1016/j.ijcard.2017.02.128. Epub 2017 Feb 27.
Several studies have associated the earlobe crease sign, discovered by Sanders T. Frank in 1973, with cardiovascular pathology, yet very few studies have focused on the antiquity of this trait, with the most ancient one thought to date back to the Roman Emperor Hadrian (76-138CE). This article presents two more cases from the Italian Renaissance in the works of the artist Andrea Mantegna (1431-1506) and examines them in a multidisciplinary fashion.
多项研究将1973年由桑德斯·T·弗兰克发现的耳垂折痕体征与心血管疾病联系起来，但很少有研究关注这一特征的古老性，人们认为最古老的案例可追溯到罗马皇帝哈德良（公元76 - 138年）时期。本文展示了艺术家安德烈亚·曼特尼亚（1431 - 1506年）作品中来自意大利文艺复兴时期的另外两个案例，并以多学科方式对其进行研究。
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