Muscatello Maria Rosaria Anna, Troili Giulia Maria, Pandolfo Gianluca, Mento Carmela, Gallo Giuseppa, Lanza Giulia, Pintaudi Basilio, Di Vieste Giacoma, Di Benedetto Antonino, Zoccali Rocco Antonio, Bruno Antonio
Dipartimento di Scienze biomediche, odontoiatriche e delle immagini morfologiche e funzionali, Università di Messina.
Dipartimento di Medicina Clinica e Sperimentale, Università di Messina.
Recenti Prog Med. 2017 Feb;108(2):77-82. doi: 10.1701/2636.27098.
The aim of this study is to evaluate the influence of negative emotions such as depression, anxiety and anger on clinical expression of type 1 diabetes, also assessing possible gender differences.
75 subjects with type 1 diabetes mellitus afferent to Diabetology Unit of the University Hospital in Messina underwent the following psychodiagnostic tests: Hamilton Rating Scale For Depression (HDRS), State-Trait Anxiety Inventory form Y (STAI-Y), State-Trait Anger Expression Inventory-2 (STAXI-2). Continuous data were expressed as mean ± standard deviation, and the comparison between groups was performed using T Student test; the data not continuous were expressed as a percentage and the differences between groups were evaluated using Chi-square test. We considered the results for values of p<0.05.
The mean age of 75 subjects (49.3% males) was 41.0±11.4 years, age of disease onset was 21.1 ± 11.8 years and mean duration of disease was 19.9±11.9 years; 30.7% of subjects were treated with CSII (Subcutaneus Insulin Infusion). Mild levels of depression (HDRS= 10.71±7.9) and anxiety (STAI-Y= 52.37±6.11) were found, whereas STAXI-2 subscales scores were within the normal range. Statistical analysis did not show significant gender differences.
Our results, according to data from literature, confirm the association between negative emotions, particularly anxiety, and diabetes. No gender differences were found.
Our results suggest the importance of investigating the association between diabetes and negative emotional states and the psychological and psychopathological dimensions which may have a potential role in the therapeutic management of diabetes.
本研究旨在评估抑郁、焦虑和愤怒等负面情绪对1型糖尿病临床表现的影响,并评估可能存在的性别差异。
墨西拿大学医院糖尿病科收治的75例1型糖尿病患者接受了以下心理诊断测试:汉密尔顿抑郁评定量表(HDRS)、状态-特质焦虑问卷Y型(STAI-Y)、状态-特质愤怒表达量表-2(STAXI-2)。连续数据以均值±标准差表示,组间比较采用t检验;非连续数据以百分比表示,组间差异采用卡方检验评估。我们将p<0.05的值视为有统计学意义。
75名受试者(49.3%为男性)的平均年龄为41.0±11.4岁,发病年龄为21.1±11.8岁,平均病程为19.9±11.9年;30.7%的受试者接受持续皮下胰岛素输注(CSII)治疗。发现受试者存在轻度抑郁(HDRS=10.71±7.9)和焦虑(STAI-Y=52.37±6.11),而STAXI-2各分量表得分在正常范围内。统计分析未显示出显著的性别差异。
根据文献数据,我们的结果证实了负面情绪,尤其是焦虑与糖尿病之间的关联。未发现性别差异。
我们的结果表明,研究糖尿病与负面情绪状态之间的关联以及可能在糖尿病治疗管理中发挥潜在作用的心理和精神病理学维度具有重要意义。