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Interference of direct oral anticoagulants in haemostasis assays: high potential for diagnostic false positives and false negatives.

作者信息

Favaloro Emmanuel J, Lippi Giuseppe

机构信息

Department of Haematology, Institute of Clinical Pathology and Medical Research (ICPMR), Sydney Centres for Thrombosis and Haemostasis, NSW Health Pathology, Westmead Hospital, Westmead, NSW, Australia.

Section of Clinical Biochemistry, University of Verona, Verona, Italy.

出版信息

Blood Transfus. 2017 Oct;15(6):491-494. doi: 10.2450/2017.0301-16. Epub 2017 Mar 7.

DOI:10.2450/2017.0301-16
PMID:28287385
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5649956/
Abstract
摘要

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Diagnosis (Berl). 2014 Dec 1;1(4):311-312. doi: 10.1515/dx-2014-0054.
2
Effect of dabigatran on a prothrombinase-based assay for detecting activated protein C resistance: an ex vivo and in vitro study in normal subjects and factor V Leiden carriers.达比加群对基于凝血酶原酶的检测活化蛋白 C 抵抗的影响:正常受试者和因子 V Leiden 携带者的离体和体外研究。
Blood Transfus. 2017 Oct;15(6):562-567. doi: 10.2450/2017.0199-16. Epub 2017 Mar 7.
3
The effect of the direct factor Xa inhibitors apixaban and rivaroxaban on haemostasis tests: a comprehensive assessment using in vitro and ex vivo samples.直接Xa因子抑制剂阿哌沙班和利伐沙班对止血试验的影响:使用体外和体内样本的综合评估
Pathology. 2016 Jan;48(1):60-71. doi: 10.1016/j.pathol.2015.11.025. Epub 2015 Dec 17.
4
The effect of dabigatran on haemostasis tests: a comprehensive assessment using in vitro and ex vivo samples.达比加群对止血检测的影响:使用体外和离体样本的综合评估。
Pathology. 2015 Jun;47(4):355-64. doi: 10.1097/PAT.0000000000000252.
5
Development of recommendations to continue anticoagulation with one of the two types of oral anticoagulants based on the identification of patients' preference.根据患者的偏好确定使用两种口服抗凝剂之一继续进行抗凝治疗的建议。
Semin Thromb Hemost. 2015 Mar;41(2):166-77. doi: 10.1055/s-0035-1546467. Epub 2015 Feb 19.
6
Laboratory testing in the era of direct or non-vitamin K antagonist oral anticoagulants: a practical guide to measuring their activity and avoiding diagnostic errors.直接口服抗凝剂或非维生素K拮抗剂口服抗凝剂时代的实验室检测:测量其活性及避免诊断错误的实用指南
Semin Thromb Hemost. 2015 Mar;41(2):208-27. doi: 10.1055/s-0035-1546827. Epub 2015 Feb 19.
7
The new or non-vitamin K antagonist oral anticoagulants: what have we learned since their debut.新型或非维生素K拮抗剂口服抗凝药:自首次亮相以来我们学到了什么。
Semin Thromb Hemost. 2015 Mar;41(2):188-94. doi: 10.1055/s-0035-1544159. Epub 2015 Feb 15.
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Recent guidelines and recommendations for laboratory assessment of the direct oral anticoagulants (DOACs): is there consensus?直接口服抗凝剂(DOACs)实验室评估的最新指南与建议:是否存在共识?
Clin Chem Lab Med. 2015 Feb;53(2):185-97. doi: 10.1515/cclm-2014-0767.
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Comparison of the efficacy and safety of new oral anticoagulants with warfarin in patients with atrial fibrillation: a meta-analysis of randomised trials.新型口服抗凝剂与华法林治疗心房颤动患者的疗效和安全性比较:随机试验的荟萃分析。
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