Schmidt Norman B, Norr Aaron M, Allan Nicholas P, Raines Amanda M, Capron Daniel W
Department of Psychology, Florida State University.
Department of Psychology, University of Southern Mississippi.
J Consult Clin Psychol. 2017 Jun;85(6):596-610. doi: 10.1037/ccp0000195. Epub 2017 Mar 13.
Anxiety sensitivity (AS) is a well-established transdiagnostic risk factor for anxiety and mood psychopathology including suicide. A variety of interventions using cognitive-behavioral skills as well as cognitive bias modification (CBM) suggest that AS can be quickly and effectively reduced in nonclinical and nontreatment seeking samples. However, it is unclear whether AS reduction protocols will have efficacy for more severe clinical samples. Moreover, the combination of cognitive-behavioral techniques with CBM focused on changing interpretation bias (CBM-I) related to AS has not been evaluated.
A patient sample with co-occurring anxiety psychopathology and active suicidal ideation (N = 74) was randomly assigned to a brief 1-session computerized treatment including: (a) psychoeducation and interoceptive exposure (i.e., cognitive anxiety sensitivity treatment [CAST]) plus CBM-I for AS; or (b) health information condition plus sham CBM for AS. Participants were assessed immediately after the 1-hr intervention as well as at 1- and 4-month follow-ups.
Consistent with hypotheses, participants in the active treatment showed significantly greater AS reduction that was maintained through follow-up (effect sizes ranged from medium to large for the overall AS and the AS subscales). Mediation analyses suggested that changes in AS mediated suicide outcomes.
In sum, these are the first findings to suggest that brief AS reduction protocols have efficacy both in terms of risk and symptom outcomes in patient samples showing active suicidal ideation. (PsycINFO Database Record
焦虑敏感性（AS）是一种公认的跨诊断风险因素，与包括自杀在内的焦虑和情绪心理病理学有关。多种使用认知行为技能以及认知偏差修正（CBM）的干预措施表明，在非临床和未寻求治疗的样本中，AS可以迅速且有效地降低。然而，尚不清楚AS降低方案对更严重的临床样本是否有效。此外，尚未评估将认知行为技术与专注于改变与AS相关的解释偏差（CBM-I）的CBM相结合的效果。
将患有共病焦虑心理病理学和活跃自杀意念的患者样本（N = 74）随机分配到一个简短的1节计算机化治疗中，包括：（a）心理教育和内感受暴露（即认知焦虑敏感性治疗[CAST]）加针对AS的CBM-I；或（b）健康信息状况加针对AS的假CBM。在1小时干预后以及1个月和4个月随访时对参与者进行评估。
与假设一致，并通过随访保持，积极治疗组的参与者AS降低幅度显著更大（总体AS及其子量表的效应大小从中等至大）。中介分析表明，AS的变化介导了自杀结果。
总之，这些是首批研究结果，表明简短的AS降低方案在显示活跃自杀意念的患者样本的风险和症状结果方面均具有疗效。（PsycINFO数据库记录）
