Oh Sang Ho, Son Sun Han, Kang Si Hyun, Kim Don-Kyu, Seo Kyung Mook, Lee Sang Yoon
1 Department of Physical Medicine and Rehabilitation, Chung-Ang University College of Medicine , Seoul, South Korea .
2 Department of Rehabilitation Medicine, Seoul National University Boramae Medical Center, Seoul, South Korea .
Metab Syndr Relat Disord. 2017 May;15(4):199-205. doi: 10.1089/met.2016.0151. Epub 2017 Mar 13.
Metabolic syndrome (MetS) significantly correlates with exercise. MetS also has an independent and inverse correlation to quality of life (QoL). However, few studies have examined the association between exercise and QoL in people with MetS. The aim of this study was to ascertain the relationship between exercise and QoL in a MetS population.
This was a cross-sectional study using public data from the Sixth Korean National Health and Nutrition Examination Survey in 2014 (n = 7550). MetS was defined on the basis of the revised National Cholesterol Education Program criteria. Demographic factors, three types of exercise (resistance, flexibility, walking), five subsets of EuroQoL (mobility, self-care, usual activities, pain/discomfort, anxiety/depression), and QoL scores (EQ-VAS), were investigated. Independent associations of each exercise on five subsets of QoL were determined using odds ratios (OR) adjusted for four demographic factors (age group, sex, weight change, and area of residence) using multivariate logistic regression analysis.
Prevalence of MetS was 26.4% and the ratio of subjects performing resistance, flexibility, or walking exercise was 17.7%, 45.8%, and 71.5% among this population, respectively. EQ-VAS of exercisers was significantly higher than that of non-exercisers in resistance, flexibility, and walking exercise. Although resistance and flexibility exercise did not correlate with any subsets of QoL, mobility and self-care were significantly associated with walking exercise (OR = 0.635, 95% CI = 0.439-0.919 and OR = 0.577, 95% CI = 0.348-0.958, respectively).
All exercisers showed higher QoL scores than non-exercisers. Among QoL subsets, mobility and self-care were independently associated with walking exercise in the MetS population. Regular walking exercise was important to higher QoL in those with MetS. This is the first clinical report to indicate that QoL could be independently influenced by walking exercise.
代谢综合征（MetS）与运动显著相关。MetS与生活质量（QoL）也存在独立的负相关。然而，很少有研究探讨MetS患者运动与QoL之间的关联。本研究的目的是确定MetS人群中运动与QoL之间的关系。
这是一项横断面研究，使用了2014年韩国第六次全国健康与营养检查调查的公共数据（n = 7550）。MetS根据修订后的国家胆固醇教育计划标准定义。调查了人口统计学因素、三种运动类型（阻力运动、柔韧性运动、步行）、欧洲五维健康量表（EQ-5D）的五个维度（移动性、自我护理、日常活动、疼痛/不适、焦虑/抑郁）以及QoL评分（EQ-VAS）。使用多因素逻辑回归分析，通过调整四个人口统计学因素（年龄组、性别、体重变化和居住地区）的比值比（OR），确定每种运动与QoL五个维度的独立关联。
MetS的患病率为26.4%，该人群中进行阻力运动、柔韧性运动或步行运动的受试者比例分别为17.7%、45.8%和71.5%。在阻力运动、柔韧性运动和步行运动中，运动者的EQ-VAS显著高于非运动者。尽管阻力运动和柔韧性运动与QoL的任何维度均无相关性，但移动性和自我护理与步行运动显著相关（OR分别为0.635，95%CI为0.439-0.919；OR为0.577，9CI为0.348-0.958）。
所有运动者的QoL评分均高于非运动者。在QoL维度中，移动性和自我护理与MetS人群的步行运动独立相关。规律的步行运动对MetS患者提高QoL很重要。这是第一份表明QoL可受步行运动独立影响的临床报告。
