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德国一家大学儿童医院中，采用快速荧光免疫测定法（Sofia系统）和快速床边检测法（BinaxNOW）对鼻咽拭子进行流感和呼吸道合胞病毒诊断，并与传统荧光免疫测定法进行比较。

Comparison of influenza and RSV diagnostic from nasopharyngeal swabs by rapid fluorescent immunoassay (Sofia system) and rapid bedside testing (BinaxNOW) vs. conventional fluorescent immunoassay in a German university children's hospital.

作者信息

Rack-Hoch Anita L, Laniado Gudrun, Hübner Johannes

机构信息

Division of Pediatric Infectious Diseases, Hauner Children's Hospital, Ludwig-Maximilians-University Munich, Lindwurmstr. 4, 80337, Munich, Germany.

出版信息

Infection. 2017 Aug;45(4):529-532. doi: 10.1007/s15010-017-1001-8. Epub 2017 Mar 13.

DOI:10.1007/s15010-017-1001-8
PMID:28290129
Abstract

The Sofia fluorescent immunoassay showed excellent sensitivity and specificity compared to conventional fluorescent immunoassay for Influenza A (Influenza B was not detected during the study period) and RSV in patients with suspected ILI (influenza-like illness). Thus the fast and easy-to-handle Sofia FIA leads to rapid and reliable diagnosis, which can be used by clinicians to avoid unnecessary antibiotic treatment and rapidly identify patients who need to be isolated upon hospital admission.

摘要

与传统荧光免疫分析法相比，Sofia荧光免疫分析法在疑似流感样疾病（ILI）患者中检测甲型流感（研究期间未检测到乙型流感）和呼吸道合胞病毒（RSV）时显示出优异的灵敏度和特异性。因此，快速且易于操作的Sofia荧光免疫分析法可实现快速可靠的诊断，临床医生可利用这一方法避免不必要的抗生素治疗，并在患者入院时迅速识别出需要隔离的患者。

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Economic analysis of rapid and sensitive polymerase chain reaction testing in the emergency department for influenza infections in children.急诊科针对儿童流感感染的快速灵敏聚合酶链反应检测的经济分析
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Comparison of the Sofia and Veritor direct antigen detection assay systems for identification of influenza viruses from patient nasopharyngeal specimens.用于从患者鼻咽标本中鉴定流感病毒的Sofia和Veritor直接抗原检测分析系统的比较。
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Evaluation of novel second-generation RSV and influenza rapid tests at the point of care.
Influenza species and subtypes circulation among hospitalized patients in Laleh hospital during two influenza seasonal (2016-2017 and 2017-2018) using a multiplex Real Time-Polymerase Chain Reaction.
在两个流感季节（2016 - 2017年和2017 - 2018年）期间，使用多重实时聚合酶链反应，对拉莱医院住院患者中流感病毒种类和亚型的流行情况进行研究。
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新型第二代呼吸道合胞病毒和流感即时检测快速检测方法的评估。
Diagn Microbiol Infect Dis. 2015 Mar;81(3):171-6. doi: 10.1016/j.diagmicrobio.2014.11.013. Epub 2014 Dec 3.
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