First experiences with model based iterative reconstructions influence on quantitative plaque volume and intensity measurements in coronary computed tomography angiography.

PURPOSE

Investigate the influence of adaptive statistical iterative reconstruction (ASIR) and the model-based IR (Veo) reconstruction algorithm in coronary computed tomography angiography (CCTA) images on quantitative measurements in coronary arteries for plaque volumes and intensities.

METHODS

Three patients had three independent dose reduced CCTA performed and reconstructed with 30% ASIR (CTDI at 6.7 mGy), 60% ASIR (CTDI 4.3 mGy) and Veo (CTDI at 1.9 mGy). Coronary plaque analysis was performed for each measured CCTA volumes, plaque burden and intensities.

RESULTS

Plaque volume and plaque burden show a decreasing tendency from ASIR to Veo as median volume for ASIR is 314 mm and 337 mm-252 mm for Veo and plaque burden is 42% and 44% for ASIR to 39% for Veo. The lumen and vessel volume decrease slightly from 30% ASIR to 60% ASIR with 498 mm-391 mm for lumen volume and vessel volume from 939 mm to 830 mm. The intensities did not change overall between the different reconstructions for either lumen or plaque.

CONCLUSION

We found a tendency of decreasing plaque volumes and plaque burden but no change in intensities with the use of low dose Veo CCTA (1.9 mGy) compared to dose reduced ASIR CCTA (6.7 mGy & 4.3 mGy), although more studies are warranted.