钌催化的2,3,3-三氟烯丙基碳酸酯的区域选择性烯丙基胺化反应

Ruthenium-catalyzed regioselective allylic amination of 2,3,3-trifluoroallylic carbonates.

作者信息

Isobe Shin-Ichi, Terasaki Shou, Hanakawa Taisyun, Mizuno Shota, Kawatsura Motoi

机构信息

Department of Chemistry, College of Humanities & Sciences, Nihon University, Sakurajosui, Setagaya-ku, Tokyo 156-8550, Japan.

出版信息

Org Biomol Chem. 2017 Apr 5;15(14):2938-2946. doi: 10.1039/c7ob00514h.

DOI:10.1039/c7ob00514h

PMID:28290580

Abstract

We demonstrated the ruthenium-catalyzed allylic amination of 2,3,3-trifluoroallylic carbonates with several types of amines. The reactions proceeded with several types of amines, and succeeded in obtaining polyfluorinated terminal alkenes possessing branched allylic amines as a single regioisomer.

摘要

我们展示了钌催化2,3,3-三氟烯丙基碳酸酯与几种胺的烯丙基胺化反应。该反应能与几种胺发生，成功得到了以单一区域异构体形式存在的带有支链烯丙基胺的多氟代末端烯烃。