Vancampfort Davy, Mugisha James, De Hert Marc, Probst Michel, Stubbs Brendon
J Phys Act Health. 2017 Jul;14(7):571-577. doi: 10.1123/jpah.2016-0507. Epub 2017 Mar 14.
Sedentary behavior is independently associated with an increased risk of poor mental health, developing cardiovascular disease (CVD) and premature mortality. Despite the knowledge that CVD is one of the leading causes of non-AIDS related premature mortality in people living with HIV (PLWH), relatively little attention has been attributed to sedentary behavior in this population. The aims of this meta-analysis were to (a) establish the pooled mean time spent sedentary, (b) investigate predictors of sedentary levels, and (c) explore differences with age- and gender-matched healthy controls.
Two independent authors searched major databases until August 2016. A random effects meta-analysis was performed.
Across 6 unique cross-sectional studies, including 9 sedentary levels, there were 523 (292 men) PLWH (age range = 37 to 58 years). PLWH spent 533 min/day (95% CI = 466 to 599) engaging in sedentary behavior. There was a trend (P = .07) for higher levels of sedentary behavior in self-report measures (551 min, 95% CI = 543 to 560, N = 4) than in objective sedentary behavior time (505 min, 95% CI = 498 to 512, N = 3). The time PLWH spend engaging in sedentary behavior is among the highest levels reported in the literature.
Given that sedentary behavior is an independent predictor of CVD, future lifestyle interventions specifically targeting the prevention of sedentary behavior in PLWH are warranted.
久坐行为与心理健康不佳、患心血管疾病（CVD）风险增加及过早死亡独立相关。尽管已知CVD是人类免疫缺陷病毒（HIV）感染者（PLWH）中非艾滋病相关过早死亡的主要原因之一，但该人群中的久坐行为相对较少受到关注。本荟萃分析的目的是：（a）确定久坐时间的合并平均时长；（b）调查久坐水平的预测因素；（c）探索与年龄和性别匹配的健康对照的差异。
两名独立作者检索主要数据库至2016年8月。进行随机效应荟萃分析。
在6项独特的横断面研究中，包括9个久坐水平，共有523名（292名男性）PLWH（年龄范围=37至58岁）。PLWH每天花533分钟（95%置信区间=466至599）久坐。自我报告测量中的久坐行为水平（551分钟，95%置信区间=543至560，N=4）高于客观久坐行为时间（505分钟，95%置信区间=498至512，N=3），存在一种趋势（P=0.07）。PLWH久坐行为的时间处于文献报道的最高水平之列。
鉴于久坐行为是CVD的独立预测因素，未来有必要开展专门针对预防PLWH久坐行为的生活方式干预。
