Recurrent respiratory papillomatosis. Clinical overview and management principles.

Recurrent respiratory papillomatosis is an uncommon clinical disorder of respiratory epithelium caused by HPV. It shares the identical viral etiology with genital condyloma and in all likelihood is transmitted at the time of birth (juvenile-onset disease) and through intimate sexual contact (adult-onset disease). The recent establishment of viral etiology modifies our concepts regarding the nature of the disease, its epidemiology, and its treatment.