Rachid Fady
RACHID: Private Practice, Geneva, Switzerland.
J Psychiatr Pract. 2017 Mar;23(2):145-147. doi: 10.1097/PRA.0000000000000214.
Depersonalization disorder (DPD) is a debilitating dissociative condition with no proven treatments. Although the pathophysiology of DPD is poorly understood, there are reports of increased excitability of the prefrontal cortex in patients with this condition. The temporo-parietal junction may also play a major role in the conscious experience of the spatial unity of the normal self and body. Repetitive transcranial magnetic stimulation has been shown in some case studies to effectively treat this condition. This report describes an additional such case, a 26-year-old man with a 6-month history of DPD who responded safely and significantly to repetitive transcranial magnetic stimulation to the right temporo-parietal junction.
人格解体障碍（DPD）是一种使人衰弱的解离性疾病，目前尚无经证实有效的治疗方法。尽管对DPD的病理生理学了解甚少，但有报告称患有这种疾病的患者前额叶皮质兴奋性增加。颞顶联合区在正常自我和身体空间统一性的意识体验中也可能起主要作用。一些案例研究表明，重复经颅磁刺激可有效治疗这种疾病。本报告描述了另外一个此类病例，一名26岁男性，有6个月的DPD病史，对右侧颞顶联合区进行重复经颅磁刺激后反应良好且安全，症状明显改善。
