[1型双相情感障碍患者缓解期功能的预测因素]
[Factors predicting functioning in type 1 bipolar patients during remission period].
作者信息
Fekih-Romdhane Feten, Homri Wided, Mrabet Ali, Labbane Raja
机构信息
Université de Tunis El Manar, Faculté de Medecine de Tunis, Tunisie; Hopital Razi, La Mannouba, Tunisie.
Université de Tunis El Manar, Faculté de Medecine de Tunis, Tunisie; Unité de surveillance épidémiologique, Direction Générale de la Santé Militaire, Tunisie.
出版信息
Pan Afr Med J. 2016 Oct 3;25:66. doi: 10.11604/pamj.2016.25.66.8532. eCollection 2016.
INTRODUCTION
Recent studies indicate that bipolar disorder is associated with a profound impairment in almost all areas of functioning. This study aims to evaluate functional recovery in type 1 bipolar patients during remission period.
METHOD
We conducted a cross-sectional study of euthymic type 1 bipolar patients followed up on an ambulatory basis. In the analysis to be reported here we used Hamilton Depression Scale, Young Mania Rating Scale (YMRS), Rosenberg Self-Esteem Scale, and Functioning Assessment Short Test (FAST).
RESULTS
More than half of the study population (53.3%) had overall functional impairment. The overall functioning was associated with age, education level, professional activity, the number of manic and depressive episodes, the number of hospitalizations, a higher HDRS score as well as with the two self-esteem subscores: "self-confidence" and "self-deprecation".
CONCLUSION
Our results suggest that a paradigm shift in the treatment of bipolar disorders should happen and that the goals of therapy should be modified from symptomatic remission to functional remission.
引言
近期研究表明，双相情感障碍几乎在所有功能领域都伴有严重损害。本研究旨在评估1型双相情感障碍患者缓解期的功能恢复情况。
方法
我们对1型双相情感障碍缓解期患者进行了一项门诊随访的横断面研究。在此报告的分析中，我们使用了汉密尔顿抑郁量表、杨氏躁狂评定量表（YMRS）、罗森伯格自尊量表和功能评估简短测试（FAST）。
结果
超过一半的研究人群（53.3%）存在整体功能损害。整体功能与年龄、教育水平、职业活动、躁狂和抑郁发作次数、住院次数、较高的HDRS评分以及两个自尊子评分：“自信”和“自我贬低”相关。
结论
我们的结果表明，双相情感障碍的治疗应发生范式转变，治疗目标应从症状缓解转变为功能缓解。
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