Silva Lea A B, Romualdo Priscilla C, Silva Raquel A B, Souza-Gugelmin Maria C M, Pazelli Luciana C, De Freitas Aldevina C, Faria Gisele, Nelson-Filho Paulo
Full professor, in the Department of Pediatric Dentistry in the School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto.
PhD student, in the Department of Pediatric Dentistry in the School of Dentistry of Ribeirão Preto, University of São Paulo, Ribeirão Preto;, Email:
Pediatr Dent. 2017 Jan 15;39(1):28-33.
The purpose of this study was to evaluate in vivo the antibacterial effect of calcium hydroxide (CH) dressings, with or without chlorhexidine (CHX), on human primary teeth with apical periodontitis.
Forty root canals in 40 children were selected. A first microbiological sample was obtained after coronal opening, and the teeth were randomly assigned to Group 1 (root canals filled with CH paste) and Group 2 (CH paste plus 1.0 percent CHX). After 30 days, the dressing was removed and the canals were allowed to remain empty for 72 hours. Subsequently, the second microbiological sample was collected. After performing microbiological tests, the data were subjected to statistical analysis to compare the two CH dressings regarding reducing the absolute levels of microorganisms and with respect to total microbial elimination. All analyses were performed with a significance level of five percent.
Both CH dressings provided a significant reduction in the number of microorganisms (anaerobic, aerobic, black-pigmented bacilli, streptococci and Streptococcus mutans) in a similar way (P>0.05). However, in terms of complete elimination of microbiota, CH paste alone exhibited greater efficacy (P<0.05).
The addition of chlorhexidine did not provide additional antimicrobial benefits compared with pure calcium hydroxide paste as an intracanal dressing in primary teeth with apical periodontitis.
本研究旨在评估含或不含洗必泰(CHX)的氢氧化钙(CH)敷料对患有根尖周炎的人类乳牙的体内抗菌效果。
选取40名儿童的40个根管。在开髓后获取第一份微生物样本,然后将牙齿随机分为第1组(根管内填充CH糊剂)和第2组(CH糊剂加1.0%的CHX)。30天后,取出敷料,使根管空置72小时。随后,收集第二份微生物样本。进行微生物检测后,对数据进行统计分析,以比较两种CH敷料在降低微生物绝对水平和完全消除微生物方面的情况。所有分析的显著性水平为5%。
两种CH敷料均以相似的方式显著减少了微生物数量(厌氧菌、需氧菌、产黑色素杆菌、链球菌和变形链球菌)(P>0.05)。然而,就完全消除微生物群而言,单独使用CH糊剂表现出更高的疗效(P<0.05)。
在患有根尖周炎的乳牙根管内使用敷料时,与单纯的氢氧化钙糊剂相比,添加洗必泰并没有提供额外的抗菌益处。