IBDM, UMR 7288, Aix-Marseille Université and CNRS, 13009 Marseille, France.
IBDM, UMR 7288, Aix-Marseille Université and CNRS, 13009 Marseille, France; Collège de France, 11 place Marcelin Berthelot, 75005 Paris, France.
Dev Cell. 2017 Mar 13;40(5):425-426. doi: 10.1016/j.devcel.2017.02.025.
What coordinates the internal leading and trailing edges in collectively migrating cells is largely unknown. In this issue of Developmental Cell, Barlan et al. (2017) delineate a Fat2/Lar planar signaling pathway at the basal, motile cell-cell contacts of Drosophila egg chamber follicle cells.
在集体迁移细胞中协调内部前缘和后缘的是什么在很大程度上是未知的。在本期《发育细胞》中,Barlan 等人(2017 年)描绘了果蝇卵室滤泡细胞基底、运动细胞-细胞接触处的 Fat2/Lar 平面信号通路。