Zalavras Charalampos G
LAC+USC Medical Center, Keck School of Medicine, University of Southern California, 1200 North State Street, GNH 3900, Los Angeles, CA 90033, USA.
Infect Dis Clin North Am. 2017 Jun;31(2):339-352. doi: 10.1016/j.idc.2017.01.005. Epub 2017 Mar 11.
Open fractures are complex injuries that are associated with increased risk for complications, such as infection and nonunion. The goals of open fracture management are prevention of infection, fracture union, and restoration of function. These goals are best achieved by careful patient and injury assessment, early administration of systemic antibiotics supplemented by local delivery of antibiotics in severe injuries, thorough surgical debridement, wound management with soft tissue coverage if needed, and stable fracture fixation.
开放性骨折是复杂的损伤，会增加诸如感染和骨不连等并发症的风险。开放性骨折治疗的目标是预防感染、促进骨折愈合以及恢复功能。通过仔细的患者和损伤评估、早期给予全身抗生素并在严重损伤时辅以局部抗生素给药、彻底的手术清创、必要时进行软组织覆盖的伤口处理以及稳定的骨折固定，能最好地实现这些目标。
