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亚洲国家糖尿病视网膜病变筛查指南的可及性与变异性

Availability and variability in guidelines on diabetic retinopathy screening in Asian countries.

作者信息

Wang Louis Zizhao, Cheung Carol Y, Tapp Robyn J, Hamzah Haslina, Tan Gavin, Ting Daniel, Lamoureux Ecosse, Wong Tien Yin

机构信息

Singapore Eye Research Institute, Singapore National Eye Centre, Singapore, Singapore.

Yong Loo Lin School of Medicine, National University of Singapore, Singapore, Singapore.

出版信息

Br J Ophthalmol. 2017 Oct;101(10):1352-1360. doi: 10.1136/bjophthalmol-2016-310002. Epub 2017 Mar 14.

Abstract

BACKGROUND

Diabetic retinopathy (DR) is a blinding yet treatable complication of diabetes. DR screening is highly cost-effective at reducing blindness. Amidst the rapidly growing diabetic population in Asia, the prevalence of DR in the region is relatively less well known.

AIMS

To review existing national DR screening guidelines of 50 countries in Asia, compare them against the International Council of Ophthalmology (ICO) guideline, and summarise the prevalence rates of DR and sight-threatening DR (STDR) in these countries.

METHODS

We systematically searched for published guidelines from the National Guideline Clearinghouse and other databases, and contacted local diabetic and ophthalmological associations of all 50 Asian countries.

RESULTS

Eleven Asian countries have published relevant guidelines, nine of which pertain to general diabetes care and two are DR-specific, covering less than half of Asia's population. The median DR prevalence among patients with diabetes is 30.5% (IQR: 23.2%-36.8%), similar to the USA and the UK. However, rates of STDR are consistently higher. All guidelines from the 11 Asian countries fulfil the ICO standard on when to start and repeat screening, except for screening interval for pregnant patients. However, only 2 of the 11 guidelines fulfil the ICO referral criteria and 6 partially fulfil. A third of the recommendations on screening process, equipment and personnel is either unavailable or incomplete.

CONCLUSIONS

Countries in Asia need to establish more comprehensive and evidence-based DR screening guidelines to facilitate the execution of robust screening programmes that could help reduce DR-related blindness, improve patient outcomes and reduce healthcare costs.

摘要

背景

糖尿病视网膜病变(DR)是一种可致盲但可治疗的糖尿病并发症。DR筛查在预防失明方面具有很高的成本效益。在亚洲糖尿病患者数量迅速增长的背景下,该地区DR的患病率相对鲜为人知。

目的

回顾亚洲50个国家现有的国家DR筛查指南,与国际眼科理事会(ICO)指南进行比较,并总结这些国家DR和威胁视力的DR(STDR)的患病率。

方法

我们系统地检索了国家指南交换中心和其他数据库中已发表的指南,并联系了亚洲所有50个国家的当地糖尿病和眼科协会。

结果

11个亚洲国家已发布相关指南,其中9个与一般糖尿病护理有关,2个是特定于DR的,覆盖不到亚洲一半的人口。糖尿病患者中DR的患病率中位数为30.5%(四分位间距:23.2%-36.8%),与美国和英国相似。然而,STDR的患病率一直较高。11个亚洲国家的所有指南在何时开始和重复筛查方面均符合ICO标准,但孕妇的筛查间隔除外。然而,11项指南中只有2项符合ICO转诊标准,6项部分符合。关于筛查流程、设备和人员的建议中有三分之一要么不可用,要么不完整。

结论

亚洲国家需要制定更全面且基于证据的DR筛查指南,以促进强有力的筛查计划的实施,这有助于减少与DR相关的失明、改善患者预后并降低医疗成本。

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