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12岁以下儿童视网膜病变的诊断:对英国糖尿病眼部筛查指南的启示

Diagnosis of retinopathy in children younger than 12 years of age: implications for the diabetic eye screening guidelines in the UK.

作者信息

Hamid A, Wharton H M, Mills A, Gibson J M, Clarke M, Dodson P M

机构信息

Departments of Diabetes and Ophthalmology, Heartlands Hospital, Birmingham, UK.

School of Health and Life Sciences, Aston University, Birmingham, UK.

出版信息

Eye (Lond). 2016 Jul;30(7):949-51. doi: 10.1038/eye.2016.59. Epub 2016 Apr 15.

DOI:10.1038/eye.2016.59
PMID:27080488
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC4941064/
Abstract

AimTo assess whether the current starting age of 12 is suitable for diabetic retinopathy (DR) screening and whether diabetes duration should be taken into account when deciding at what age to start screening patients.Materials and methodsA retrospective analysis of 143 patients aged 12 years or younger who attended diabetic eye screening for the first time in the Birmingham, Solihull and Black Country Diabetic Eye Screening Programme was performed.ResultsThe mean age of the patients was 10.7 (7-12) years with 73 out of 143 aged below 12 years and 70 were 12 years of age. 98% had type 1 diabetes and mean diabetes duration was 5 (1 month-11 years) years. For those younger than 12 years, 7/73 (9.6%) had background DR (BDR), of these mean diabetes duration was 7 years (6-8). The youngest patient to present with DR was aged 8 years. In those aged 12 years, 5/70 (7.1%) had BDR; of these mean diabetes duration was 8 years (6-11). No patient developed DR before 6 years duration in either group.ConclusionsThe results show that no patient younger than the age of 12 had sight-threatening DR (STDR), but BDR was identified. Based on the current mission statement of the Diabetic Eye Screening Programme to identify STDR, 12 years of age is confirmed as the right age to start screening, but if it is important to diabetic management to identify first development of DR, then screening should begin after 6 years of diabetes diagnosis.

摘要

目的

评估目前12岁的起始筛查年龄是否适用于糖尿病视网膜病变(DR)筛查,以及在决定患者开始筛查的年龄时是否应考虑糖尿病病程。

材料与方法

对在伯明翰、索利赫尔和黑乡糖尿病眼部筛查项目中首次参加糖尿病眼部筛查的143名12岁及以下患者进行回顾性分析。

结果

患者的平均年龄为10.7(7 - 12)岁,143名患者中有73名年龄低于12岁,70名患者为12岁。98%的患者患有1型糖尿病,平均糖尿病病程为5(1个月 - 11年)年。对于年龄小于12岁的患者,7/73(9.6%)患有轻度非增殖性糖尿病视网膜病变(BDR),其中平均糖尿病病程为7年(6 - 8年)。出现DR的最年轻患者为8岁。在12岁的患者中,5/70(7.1%)患有BDR;其中平均糖尿病病程为8年(6 - 11年)。两组中均无患者在病程6年之前出现DR。

结论

结果表明,年龄小于12岁的患者无威胁视力的糖尿病视网膜病变(STDR),但发现了BDR。基于糖尿病眼部筛查项目目前识别STDR的任务声明,确认12岁是开始筛查的合适年龄,但如果在糖尿病管理中识别DR的首次发生很重要,那么应在糖尿病诊断6年后开始筛查。

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