Aljarallah Khalid M
Department of Medical Laboratory Sciences, College of Applied Medical Sciences, Majmaah University, Majmaah, KSA.
Int J Health Sci (Qassim). 2017 Jan-Mar;11(1):1-10.
-associated disease continues to be one of the leading health concerns worldwide. is considered as a causative agent of nosocomial diarrhea that causes serious infection, which may result in death. The incidences of infection (CDI) in developed countries have become increasingly high which may be attributed to the emergence of newer epidemic strains, extensive use of antibiotics, and limited alternative therapies. The available treatment options against CDI are expensive and promote resistance. Therefore, there is urgent need for new approaches to meet these challenges. This review discusses the current understanding of CDI, the existing clinical treatment strategies and future potential options as antidifficile agents based on the available published works.
相关疾病仍然是全球主要的健康问题之一。它被认为是导致医院感染性腹泻的病原体，可引发严重感染，甚至可能导致死亡。发达国家艰难梭菌感染（CDI）的发病率日益升高，这可能归因于新型流行菌株的出现、抗生素的广泛使用以及替代疗法有限。针对CDI的现有治疗方案价格昂贵且会促进耐药性。因此，迫切需要新的方法来应对这些挑战。本综述基于已发表的现有研究成果，讨论了对CDI的当前认识、现有的临床治疗策略以及未来作为抗艰难梭菌药物的潜在选择。
