Nomura Tadashi, Sakakibara Shunsuke, Moriwaki Aya, Kawamoto Teruya, Suzuki Satoshi, Ishimura Takeshi, Hashikawa Kazunobu, Terashi Hiroto
Department of Plastic Surgery, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.
Department of Orthopaedic Surgery, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.
Eplasty. 2017 Feb 21;17:e6. eCollection 2017.
Myxofibrosarcoma (MFS) is a relatively rare tumor that is histologically characterized by myxoid stroma and spindle cell proliferation. This tumor most commonly arises as a slow growing, enlarging painless mass in the extremities of elderly patients. We report a case of a primary, low-grade MFS in the rectus abdominis muscle infiltrating the abdominal cavity of a 75-year-old man. The patient underwent a wide excision of the right abdominal wall mass with a 3-cm surgical margin from the scar due to a biopsy. The tumor infiltrated the urinary bladder, peritoneum, and external iliac vessels. Twenty-six months after the initial operation, he had recurrences in his abdominal wall, urinary bladder, and right iliac vessels. To our knowledge, primary MFS of the muscle in the abdomen has not been documented previously. Although this case was histopathologically classified as a low-grade tumor, it infiltrated the abdominal cavity. The tumor is suspected to have penetrated the abdominal cavity below the linea arcuata, which lacks the posterior sheath of the rectus abdominis muscle; from there, it could easily spread without being blocked by any biological barriers.
黏液纤维肉瘤(MFS)是一种相对罕见的肿瘤,其组织学特征为黏液样基质和梭形细胞增殖。这种肿瘤最常表现为老年患者四肢缓慢生长、逐渐增大的无痛性肿块。我们报告一例75岁男性腹直肌原发性低级别MFS浸润腹腔的病例。因活检,患者接受了右侧腹壁肿块广泛切除,手术切缘距瘢痕3厘米。肿瘤浸润了膀胱、腹膜和髂外血管。初次手术后26个月,他的腹壁、膀胱和右髂血管出现复发。据我们所知,此前尚未有腹部肌肉原发性MFS的记录。尽管该病例在组织病理学上被分类为低级别肿瘤,但它浸润了腹腔。怀疑肿瘤穿透了腹直肌后鞘缺失的弓状线以下的腹腔;从那里,它可以很容易地扩散而不受任何生物屏障的阻挡。