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产后脑静脉血栓形成的临床与治疗方面

[Clinical and therapeutic aspects of post-partum cerebral thrombophlebites].

作者信息

Hafed Barhoumi Mohamed, Houcem Ragmoun, Wassim Saidi, Taieb Guizani, Waddah Manssouri, Mohamed Liouane, Ridha Fatnassi Mohamed

机构信息

Service d'Anesthésie Réanimation, CHU Ibn El Jazzar, Kairouan, Tunisie.

Service de Gynécologie Obstétrique- CHU Ibn El Jazzar, Kairouan, Tunisie.

出版信息

Pan Afr Med J. 2016 Dec 21;25:248. doi: 10.11604/pamj.2016.25.248.9576. eCollection 2016.

Abstract

Cerebral thrombophlebites are rare but life-threatening conditions (1/5000 births). Pregnancy and postpartum are predisposing factors: clinical presentation vary and may be misleading, dominated by headaches, convulsions and neurological deficits but showing no specific features. Physical examination often generates informations unavailable and misleading because cerebral thrombophlebites share symptoms with other affections. A definitive diagnosis can be made only neuroradiologically. Brain MRI is currently the reference method; it allows visualization of the venous thrombus and its evolution. The treatment of cerebral thrombophlebites is essentially medical based on anticoagulant drugs. We here report four cases with post partum cerebral thrombophlebites. The aim of our study and review of the literature is to highlight the importance of early diagnosis and adequate therapy.

摘要

脑静脉血栓形成虽罕见但危及生命(发生率为1/5000活产)。妊娠和产后是诱发因素:临床表现多样且可能具有误导性,以头痛、惊厥和神经功能缺损为主,但无特异性特征。体格检查往往得出不可靠且具误导性的信息,因为脑静脉血栓形成与其他疾病有共同症状。只有通过神经放射学检查才能做出明确诊断。脑磁共振成像(MRI)是目前的参考方法;它能显示静脉血栓及其演变情况。脑静脉血栓形成的治疗主要是基于抗凝药物的药物治疗。我们在此报告4例产后脑静脉血栓形成病例。我们开展本研究并回顾文献的目的是强调早期诊断和适当治疗的重要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9624/5337296/91dbc487022e/PAMJ-25-248-g001.jpg

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