寡免疫性狼疮性肾炎：是必然还是巧合？
Pauci-immune lupus nephritis: possibility or co-incidence?
作者信息
Cansu Döndü Üsküdar, Temiz Gökhan, Açıkalın Mustafa F, Korkmaz Cengiz
机构信息
Division of Rheumatology, Department of Internal Medicine, Eskişehir Osmangazi University School of Medicine, Eskişehir, Turkey.
Division of Nephrology, Department of Internal Medicine, Eskişehir Osmangazi University School of Medicine, Eskişehir, Turkey.
出版信息
Eur J Rheumatol. 2017 Mar;4(1):73-75. doi: 10.5152/eurjrheum.2016.013. Epub 2017 Mar 1.
Abstract
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized with immune complex formation and renal involvement of lupus and may include several kinds of pathological conditions, but mostly, it is associated with immune complex-induced glomerular disease. Pauci-immune lupus nephritis is a very rare condition. We describe a 45-year-old female patient with pauci-immune crescentic necrotizing lupus nephritis and briefly discuss the possible mechanism and pathogenesis.
摘要
系统性红斑狼疮（SLE）是一种慢性自身免疫性疾病，其特征为免疫复合物形成以及狼疮的肾脏受累，可能包括多种病理状况，但大多数情况下，它与免疫复合物诱导的肾小球疾病相关。寡免疫性狼疮性肾炎是一种非常罕见的病症。我们描述了一名患有寡免疫性新月体坏死性狼疮性肾炎的45岁女性患者，并简要讨论了可能的机制和发病原理。
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本文引用的文献
1
The role of neutrophils in the pathogenesis of systemic lupus erythematosus.中性粒细胞在系统性红斑狼疮发病机制中的作用。
Curr Opin Rheumatol. 2015 Sep;27(5):448-53. doi: 10.1097/BOR.0000000000000197.
2
Predictive role of urinary neutrophil gelatinase-associated lipocalin in lupus nephritis.尿中性粒细胞明胶酶相关脂质运载蛋白在狼疮性肾炎中的预测作用。
Lupus. 2015 Feb;24(2):138-46. doi: 10.1177/0961203314550225. Epub 2014 Sep 8.
3
Kidney disease in lupus is not always 'lupus nephritis'.狼疮性肾病并不总是“狼疮性肾炎”。
Arthritis Res Ther. 2013 Mar 1;15(2):108. doi: 10.1186/ar4166.
4
5
ANCA-negative pauci-immune crescentic glomerulonephritis.抗中性粒细胞胞浆抗体阴性寡免疫性新月体性肾小球肾炎
Nat Rev Nephrol. 2009 Jun;5(6):313-8. doi: 10.1038/nrneph.2009.67. Epub 2009 Apr 28.
6
Necrotizing and crescentic lupus nephritis with antineutrophil cytoplasmic antibody seropositivity.伴有抗中性粒细胞胞浆抗体血清阳性的坏死性和新月形狼疮性肾炎。
Clin J Am Soc Nephrol. 2008 May;3(3):682-90. doi: 10.2215/CJN.04391007. Epub 2008 Feb 20.
7
Class IV-S versus class IV-G lupus nephritis: clinical and morphologic differences suggesting different pathogenesis.IV-S型与IV-G型狼疮性肾炎：提示不同发病机制的临床和形态学差异
Kidney Int. 2005 Nov;68(5):2288-97. doi: 10.1111/j.1523-1755.2005.00688.x.
8
ANCA-negative pauci-immune renal vasculitis: histology and outcome.抗中性粒细胞胞浆抗体阴性少免疫性肾血管炎：组织学与预后
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9
Antineutrophil cytoplasmic autoantibodies in systemic lupus erythematosus.系统性红斑狼疮中的抗中性粒细胞胞浆自身抗体
Lupus. 2003;12(9):651-8. doi: 10.1191/0961203303lu456rr.
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Am J Kidney Dis. 2000 Jun;35(6):1193-206. doi: 10.1016/s0272-6386(00)70058-8.
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