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表现为单纯先天性上睑下垂的早发型双侧青少年型重症肌无力

Early onset bilateral juvenile myasthenia gravis masquerading as simple congenital ptosis.

作者信息

Alam Md Shahid, Devi Nivean Pratheeba

机构信息

Department of Orbit, Oculoplasty, Reconstructive and Aesthetic services, Sankara Nethralaya, Medical Research Foundation, Chennai, Tamil Nadu, India.

M.N. Eye Hospital, Chennai, India.

出版信息

GMS Ophthalmol Cases. 2017 Mar 7;7:Doc07. doi: 10.3205/oc000058. eCollection 2017.

Abstract

Myasthenia gravis is an autoimmune disorder affecting the neuromuscular junction. Ocular myasthenia gravis presents as ptosis with extraocular motility restriction and is prone to be misdiagnosed as third nerve palsy or congenital or aponeurotic ptosis. Juvenile ocular myasthenia gravis in very young children is difficult to diagnose and can be easily labeled as a case of congenital ptosis, the more so when the condition is bilateral. We present a case of a two-year-old child who presented with bilateral ptosis and was diagnosed as a case of simple congenital ptosis elsewhere with the advice to undergo tarsofrontalis sling surgery. The child was diagnosed with juvenile myasthenia gravis on thorough history, examination, and systemic evaluation and was started on anti-myasthenic treatment.

摘要

重症肌无力是一种影响神经肌肉接头的自身免疫性疾病。眼肌型重症肌无力表现为上睑下垂伴眼球运动受限,容易被误诊为动眼神经麻痹或先天性或腱膜性上睑下垂。婴幼儿期的青少年眼肌型重症肌无力很难诊断,很容易被诊断为先天性上睑下垂,双侧发病时更是如此。我们报告一例两岁儿童,该患儿表现为双侧上睑下垂,在其他地方被诊断为单纯先天性上睑下垂,并建议接受额肌悬吊手术。通过详细的病史、检查和全身评估,该患儿被诊断为青少年型重症肌无力,并开始接受抗重症肌无力治疗。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/845a/5343208/eea327adc106/OC-07-07-g-001.jpg

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