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[伴有骨关节炎体征的膝关节疼痛]

[Knee joint pain with signs of arthrosis].

作者信息

Bender T T A, Marinova M, Radbruch L, Conrad R, Jobst D, Mücke M

机构信息

Zentrum für seltene Erkrankungen Bonn, Universitätsklinikum Bonn, Bonn, Deutschland.

Radiologische Klinik, Universitätsklinikum Bonn, Bonn, Deutschland.

出版信息

Schmerz. 2017 Jun;31(3):319-333. doi: 10.1007/s00482-017-0199-9.

DOI:10.1007/s00482-017-0199-9
PMID:28293735
Abstract

Chronic pain in the knee joint is most commonly caused by osteoarthritis, especially in elderly patients but can be due to other causes, such as rheumatoid arthritis. The diagnostics include an exact patient medical history and a clinical examination, which often already provide clear indications of the cause of the knee pain. Subsequently, further diagnostics can then be considered, such as radiological procedures and laboratory diagnostics. The treatment is determined by the cause and the individual patient and aims to reduce pain and to preserve the mobility of the joint. Generally, therapy consists of pain management and physiotherapy as well as alternative therapeutic procedures, mostly in combination. Proximal tibial opening wedge osteotomy can be useful; however, partial or total knee arthroplasty should only be considered when conservative treatment options have been exhausted.

摘要

膝关节慢性疼痛最常见的原因是骨关节炎,尤其是在老年患者中,但也可能由其他原因引起,如类风湿性关节炎。诊断包括详细的患者病史和临床检查,这通常已经能提供膝关节疼痛原因的明确线索。随后,可以考虑进一步的诊断方法,如放射学检查和实验室诊断。治疗方法取决于病因和个体患者,旨在减轻疼痛并保持关节活动度。一般来说,治疗包括疼痛管理、物理治疗以及其他治疗方法,大多是综合使用。胫骨近端开放楔形截骨术可能有用;然而,只有在保守治疗方案都用尽时才应考虑部分或全膝关节置换术。

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Schmerz. 2023 Dec;37(6):413-425. doi: 10.1007/s00482-023-00739-0. Epub 2023 Jul 28.

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Efficacy of Tailored Exercise Therapy on Physical Functioning in Patients With Knee Osteoarthritis and Comorbidity: A Randomized Controlled Trial.量身定制的运动疗法对膝骨关节炎合并症患者身体功能的疗效:一项随机对照试验。
Arthritis Care Res (Hoboken). 2017 Jun;69(6):807-816. doi: 10.1002/acr.23013. Epub 2017 Apr 24.
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Genu Valgum and Flat Feet in Children With Healthy and Excessive Body Weight.体重正常和超重儿童的膝外翻与扁平足
Pediatr Phys Ther. 2016 Summer;28(2):200-6. doi: 10.1097/PEP.0000000000000246.
3
Comparative pain reduction of oral non-steroidal anti-inflammatory drugs and opioids for knee osteoarthritis: systematic analytic review.
口服非甾体抗炎药和阿片类药物治疗膝骨关节炎的镇痛效果比较:系统分析综述。
Osteoarthritis Cartilage. 2016 Jun;24(6):962-72. doi: 10.1016/j.joca.2016.01.135. Epub 2016 Feb 1.
4
Pulsed electromagnetic fields in knee osteoarthritis: a double blind, placebo-controlled, randomized clinical trial.脉冲电磁场治疗膝骨关节炎:一项双盲、安慰剂对照、随机临床试验。
Rheumatology (Oxford). 2016 Apr;55(4):755-62. doi: 10.1093/rheumatology/kev426. Epub 2015 Dec 24.
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Why does the gout attack stop? A roadmap for the immune pathogenesis of gout.为什么痛风发作会停止?痛风免疫发病机制的研究进展。
RMD Open. 2015 Aug 15;1(Suppl 1):e000046. doi: 10.1136/rmdopen-2015-000046. eCollection 2015.
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An investigation of the added value of an ACPA multiplex assay in an early rheumatoid arthritis setting.一项关于抗环瓜氨酸肽(ACPA)多重检测在早期类风湿关节炎环境中的附加值的调查。
Arthritis Res Ther. 2015 Oct 5;17:276. doi: 10.1186/s13075-015-0786-z.
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Synovitis and the risk of knee osteoarthritis: the MOST Study.滑膜炎与膝关节骨关节炎风险:MOST研究
Osteoarthritis Cartilage. 2016 Mar;24(3):458-64. doi: 10.1016/j.joca.2015.09.013. Epub 2015 Sep 30.
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[Recommendations of the updated LONTS guidelines. Long-term opioid therapy for chronic noncancer pain].[更新后的《长期阿片类药物治疗慢性非癌性疼痛指南》的建议]
Schmerz. 2015 Feb;29(1):109-30. doi: 10.1007/s00482-014-1463-x.
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Comparative effectiveness of pharmacologic interventions for knee osteoarthritis: a systematic review and network meta-analysis.药物干预治疗膝骨关节炎的疗效比较:系统评价和网络荟萃分析。
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10
[Opioids in chronic noncancer pain-are opioids superior to nonopioid analgesics? A systematic review and meta-analysis of efficacy, tolerability and safety in randomized head-to-head comparisons of opioids versus nonopioid analgesics of at least four week's duration].[慢性非癌性疼痛中的阿片类药物——阿片类药物优于非阿片类镇痛药吗?对阿片类药物与非阿片类镇痛药至少持续四周的随机直接比较中的疗效、耐受性和安全性的系统评价与荟萃分析]
Schmerz. 2015 Feb;29(1):85-95. doi: 10.1007/s00482-014-1436-0.