Tilavberdiev S A, Denning D W, Klimko N N
Republican Center of Control of AIDS, Tashkent, Uzbekistan.
The University of Manchester, Manchester, UK.
Eur J Clin Microbiol Infect Dis. 2017 Jun;36(6):925-929. doi: 10.1007/s10096-017-2926-7. Epub 2017 Mar 14.
We have undertaken the first and preliminary estimation of severe and chronic mycotic diseases in the Republic of Uzbekistan, using a model proposed by LIFE (Leading International Fungal Education). Calculation was carried out based on data from 2014. Published results describing mycoses in Uzbekistan were identified. In the absence of published or official data, information about the frequency of mycoses from scientific literature elsewhere in groups at risk of development of fungal infections were taken into account. We also utilized methodology used in analogous estimations of mycoses in the Russian Federation. We estimate that of the 30.8 million population, 536,978 people (1.8% of the population) were affected by severe and chronic mycotic diseases. In 2014, there were 12,351 cases of acute invasive fungal diseases and 524,627 cases of chronic fungal diseases, including 1,941 cases of chronic pulmonary aspergillosis. The most frequent problems were recurrent vulvovaginal candidiasis (513,600 cases), trichophytosis of the scalp (6,414), and relapsed oral candidiasis (4,950). Results of the investigation indicate a significant prevalence of mycoses in the Republic of Uzbekistan.
我们采用了由“国际真菌教育领军者”（LIFE）提出的模型，对乌兹别克斯坦共和国的严重和慢性真菌病进行了首次初步评估。计算是基于2014年的数据进行的。我们查找了已发表的描述乌兹别克斯坦真菌病情况的结果。在缺乏已发表数据或官方数据的情况下，我们考虑了来自其他地方科学文献中关于真菌感染高危人群中真菌病发病率的信息。我们还采用了俄罗斯联邦在真菌病类似评估中使用的方法。我们估计，在3080万人口中，有536978人（占人口的1.8%）受到严重和慢性真菌病的影响。2014年，有12351例急性侵袭性真菌病病例和524627例慢性真菌病病例，其中包括1941例慢性肺曲霉病病例。最常见的问题是复发性外阴阴道念珠菌病（513600例）、头皮癣（6414例）和复发性口腔念珠菌病（4950例）。调查结果表明真菌病在乌兹别克斯坦共和国的患病率很高。
