School of Nursing, Midwifery and Paramedicine, Curtin University, Bentley, WA, Australia.
Wound Management Innovation Cooperative Research Centre (WMI CRC).
Int Wound J. 2017 Dec;14(6):950-954. doi: 10.1111/iwj.12737. Epub 2017 Mar 15.
There is a paucity of evidence surrounding the use of negative pressure wound therapy (NPWT) in patients receiving anticoagulant medication. Guidelines generally recommend caution regarding the use of NPWT in anticoagulated patients in general, but areas of particular risk are frequently not highlighted. The US Food and Drug Authority (FDA) reported six mortalities between 2009 and 2011 in patients receiving NPWT. These mortalities were associated with the use of NPWT over vascular graft sites. The coagulation status of these patients was not reported. It is the authors' recommendation that guidelines regarding the use of NPWT in anticoagulated patients highlight specific clinical situations of risk, although there is insufficient evidence to support the avoidance of NPWT in anticoagulated patients in general.
关于正在接受抗凝药物治疗的患者使用负压伤口治疗(NPWT)的证据很少。一般来说,指南建议在抗凝患者中使用 NPWT 时要谨慎,但经常没有突出特别危险的领域。美国食品和药物管理局(FDA)报告称,在 2009 年至 2011 年期间,有 6 名接受 NPWT 的患者死亡。这些死亡与 NPWT 在血管移植物部位的使用有关。这些患者的凝血状态未被报道。作者建议,关于在抗凝患者中使用 NPWT 的指南应突出特定的危险临床情况,尽管没有足够的证据支持一般避免在抗凝患者中使用 NPWT。