Schmalz Gerhard, Wendorff Horst, Marcinkowski Anna, Weinreich Gerhard, Teschler Helmut, Haak Rainer, Sommerwerck Urte, Ziebolz Dirk
Department of Cariology, Endodontology and Periodontology, University of Leipzig, Leipzig, Germany.
Department of Pneumology, Ruhrlandklinik, West German Lung Center, University Hospital Essen, University Duisburg-Essen, Essen, Germany.
Clin Respir J. 2018 Feb;12(2):731-737. doi: 10.1111/crj.12625. Epub 2017 Mar 26.
Patients after lung transplantation (LuTx) were found to present oral health deficiencies. The investigation of potentially underlying or influencing factors appears to be of clinical relevance.
Aim of this study was to evaluate the oral health related quality of life (OHRQoL) in a group of patients after LuTx and compare this to a healthy control group (HC). Furthermore, the influence of dental and periodontal condition, as well as specific factors like immunosuppression, time after LuTx and causal underlying disease should be investigated.
The OHRQoL was assessed using the German short form of the Oral Health Impact Profile (OHIP G14). Dental examination included the decayed (D-), missing (M-), and filled (F-) teeth index (DMF-T). Periodontal condition was classified based on clinical attachment loss and/or pocket depth as no/mild or moderate/severe periodontitis.
Mann-Whitney-U-test, Kruskal-Wallis test (P < .05).
A total of 60 patients after LuTx and 70 HC were included. The DMF-T, D-T, and M-T as well as periodontal disease severity was significantly higher in LuTx group (P < .01). The OHIP G14 differed neither clinically relevant, nor statistically significant (LuTx: 1.70 ± 2.70, HC: 1.54 ± 2.86, P = .15). While in HC the DMF-T, M-T, and periodontal condition had an influence on OHIP G14 values (P < .05), in LuTx no influence was detected for dental and periodontal condition as well as specific factors investigated.
The oral health perception of LuTx patients does not reflect the apparent oral health deficiencies. Consequently, sensitization and motivation for an increased dental behavior is needed.
肺移植（LuTx）术后患者存在口腔健康缺陷。对潜在的相关因素进行调查似乎具有临床意义。
本研究旨在评估一组肺移植术后患者的口腔健康相关生活质量（OHRQoL），并与健康对照组（HC）进行比较。此外，还应研究牙齿和牙周状况的影响，以及免疫抑制、肺移植术后时间和潜在病因等特定因素的影响。
使用德国版简化口腔健康影响程度量表（OHIP G14）评估OHRQoL。牙科检查包括龋失补牙指数（DMF-T）。根据临床附着丧失和/或牙周袋深度将牙周状况分为无/轻度或中度/重度牙周炎。
采用曼-惠特尼U检验、克鲁斯卡尔-沃利斯检验（P < 0.05）。
共纳入60例肺移植术后患者和70例健康对照者。肺移植组的DMF-T、D-T和M-T以及牙周疾病严重程度显著更高（P < 0.01）。OHIP G14在临床相关性和统计学意义上均无差异（肺移植组：1.70 ± 2.70，健康对照组：1.54 ± 2.86，P = 0.15）。在健康对照组中，DMF-T、M-T和牙周状况对OHIP G14值有影响（P < 0.05），而在肺移植组中，未检测到牙齿和牙周状况以及所研究的特定因素有影响。
肺移植患者的口腔健康认知并未反映出明显的口腔健康缺陷。因此，需要提高对口腔护理行为的认知并激发积极性。
