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肝移植前后不同患者的口腔健康相关生活质量取决于口腔和牙周健康状况。

Oral health-related quality of life depending on dental and periodontal health in different patients before and after liver transplantation.

机构信息

Department of Cariology, Endodontology and Periodontology, University Medical Center Leipzig, Liebigstr. 10-14, 04103, Leipzig, Germany.

Department of General, Visceral and Pediatric Surgery, University Medical Center, Goettingen, Germany.

出版信息

Clin Oral Investig. 2018 Jun;22(5):2039-2045. doi: 10.1007/s00784-017-2298-5. Epub 2017 Dec 14.

Abstract

BACKGROUND

The aim of this study was to evaluate the oral health-related quality of life (OHRQoL) depending on dental and periodontal health of different patients before and after liver transplantation (pre- and postLTx) compared to a healthy control group (HC).

METHODS

OHRQoL was rated using the German short form of Oral Health Impact Profile (OHIP G14). To estimate dental health, the decayed (D-T), missing (M-T), and filled (F-T) teeth index (DMF-T) was used. Periodontal health was classified as healthy/mild, moderate, or severe periodontitis. The following statistics are used: Mann-Whitney U test, Kruskal-Wallis test, chi-square test, and Fisher test (α = 5%).

RESULTS

A total of 24 preLTx, 47 postLTx, and 75 HC patients were included. Significant differences in DMF-T, D-T, M-T, and F-T scores were detected between groups (p < 0.001). Prevalence of periodontitis was comparable between groups (p = 0.340). OHRQoL was reduced in pre- and postLTx (OHIP G14 preLTx 4.2 [1.5; 0-4.0], postLTx 4.1 [1; 0-5.0], HC 1.4 [0; 0-2.0]; p = 0.003), without associations to their oral status (p > 0.05).

CONCLUSIONS

These preliminary findings show a reduced OHRQoL without associations to their oral status, which might indicate an influence of potential disease-related factors on OHRQoL. Further studies with larger groups are necessary to verify this observation.

CLINICAL RELEVANCE

A special dental care of patients before and after LTx is needed, including a comprehensive assessment of the individual patient's OHRQoL.

摘要

背景

本研究旨在评估不同患者在肝移植前后(移植前和移植后)的口腔健康相关生活质量(OHRQoL),并与健康对照组(HC)进行比较。

方法

使用德国口腔健康影响简表(OHIP G14)的短表评估 OHRQoL。为了评估牙齿健康,使用了龋齿(D-T)、缺失(M-T)和填充(F-T)牙齿指数(DMF-T)。牙周健康分为健康/轻度、中度或重度牙周炎。使用 Mann-Whitney U 检验、Kruskal-Wallis 检验、卡方检验和 Fisher 检验(α=5%)。

结果

共纳入 24 例移植前、47 例移植后和 75 例 HC 患者。组间 DMF-T、D-T、M-T 和 F-T 评分存在显著差异(p<0.001)。组间牙周炎的患病率相似(p=0.340)。移植前和移植后 OHRQoL 均降低(OHIP G14 移植前 4.2[1.5;0-4.0],移植后 4.1[1;0-5.0],HC 1.4[0;0-2.0];p=0.003),与口腔状况无关(p>0.05)。

结论

这些初步结果表明,OHRQoL 降低与口腔状况无关,这可能表明潜在疾病相关因素对 OHRQoL 的影响。需要进一步的大样本研究来验证这一观察结果。

临床意义

肝移植前后患者需要特殊的口腔护理,包括对患者 OHRQoL 的全面评估。

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