Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria.
High Field MR Center, Medical University of Vienna, Vienna, Austria.
Magn Reson Med. 2018 Jan;79(1):588-592. doi: 10.1002/mrm.26645. Epub 2017 Mar 10.
To demonstrate a dedicated setup for ultrahigh resolution MR imaging of the human finger in vivo.
A radiofrequency coil was designed for optimized signal homogeneity and sensitivity in the finger at ultrahigh magnetic field strength (7 T), providing high measurement sensitivity. Imaging sequences (2D turbo-spin echo (TSE) and 3D magnetization-prepared rapid acquisition gradient echo (MPRAGE)) were adapted for high spatial resolution and good contrast of different tissues in the finger, while keeping acquisition time below 10 minutes. Data was postprocessed to display finger structures in three dimensions.
3D MPRAGE data with isotropic resolution of 200 µm, along with 2D TSE images with in-plane resolutions of 58 × 78 µm and 100 × 97 µm , allowed clear identification of various anatomical features such as bone and bone marrow, tendons and annular ligaments, cartilage, arteries and veins, nerves, and Pacinian corpuscles.
Using this dedicated finger coil at 7 T, together with adapted acquisition sequences, it is possible to depict the internal structures of the human finger in vivo within patient-compatible measurement time. It may serve as a tool for diagnosis and treatment monitoring in pathologies ranging from inflammatory or erosive joint diseases to injuries of tendons and ligaments to nervous or vascular disorders in the finger. Magn Reson Med 79:588-592, 2018. © 2017 The Authors Magnetic Resonance in Medicine published by Wiley Periodicals, Inc. on behalf of International Society for Magnetic Resonance in Medicine. This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
展示一种用于人体手指超高分辨率磁共振成像的专用装置。
设计了一种射频线圈，用于在超高磁场强度（7T）下优化手指的信号均匀性和灵敏度，提供高测量灵敏度。成像序列（2D 涡轮自旋回波（TSE）和 3D 磁化准备快速获取梯度回波（MPRAGE））适用于手指中不同组织的高空间分辨率和良好对比度，同时保持采集时间在 10 分钟以下。对数据进行后处理以三维显示手指结构。
具有 200µm 各向同性分辨率的 3D MPRAGE 数据，以及具有 58×78µm 和 100×97µm 平面分辨率的 2D TSE 图像，能够清晰识别各种解剖特征，如骨和骨髓、肌腱和环形韧带、软骨、动脉和静脉、神经和Pacinian 小体。
在 7T 下使用这种专用手指线圈和适应的采集序列，可以在患者可接受的测量时间内描绘人体手指的内部结构。它可以作为从炎症或侵蚀性关节疾病到肌腱和韧带损伤到手指神经或血管疾病等各种疾病的诊断和治疗监测工具。磁共振医学 79：588-592，2018。© 2017 作者磁共振医学由 Wiley 期刊出版公司代表国际磁共振医学学会出版。这是在知识共享署名许可条款下的许可，允许在任何媒介中使用、分发和复制原作，只要原作者被正确引用。
