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特比萘芬-氟苯尼考-醋酸倍他米松耳用凝胶对患有急性外耳炎的犬及其主人生活质量的影响。

Impact of a terbinafine-florfenicol-betamethasone acetate otic gel on the quality of life of dogs with acute otitis externa and their owners.

作者信息

Noli Chiara, Sartori Roberta, Cena Tiziana

机构信息

Servizi Dermatologici Veterinari, Strada Bedale della Ressia 2, Peveragno, CN, Italy.

Servizi Dermatologici Veterinari, Via Sporting Mirasole 39, Opera, MI, Italy.

出版信息

Vet Dermatol. 2017 Aug;28(4):386-e90. doi: 10.1111/vde.12433. Epub 2017 Mar 15.

DOI:10.1111/vde.12433
PMID:28295766
Abstract

BACKGROUND

Treatment of canine otitis externa with owner-administered products can be difficult.

OBJECTIVES

To evaluate otic treatment administered by a veterinarian on quality of life (QoL) of dogs with otitis externa and their owners, and on clinical and cytology parameters of otitis; compared to an owner-administered treatment.

ANIMALS

Fifty client-owned dogs randomly randomized into two groups and treated for 2 weeks.

METHODS

Veterinarians treated Group A dogs with a veterinary licensed otic gel on two occasions at a 1 week interval; owners treated Group B dogs once daily with a veterinary licensed otic drop based product along with twice weekly cleaning. Veterinarians evaluated otitis with the OTI-3 scale and semi-quantitative cytological examination on days 0, 7, 14 and 28. At each visit, owners assessed QoL with a validated questionnaire and pruritus with a Visual Analog Scale. Scores before and after treatment of each group, and differences between groups were analysed statistically.

RESULTS

In both groups, all parameters improved significantly. There was a significantly higher improvement of QoL scores, for dogs and owners, in Group A, compared to Group B at all time points (P < 0.05), except for owner QoL on Day 28. There was no difference in improvement of OTI-3 between groups at any time point, whereas Group A cytology scores and pruritus improved significantly more by Day 7 (P = 0.0026 and P = 0.0294, respectively).

CONCLUSION

A veterinarian-administered otic gel provided equivalent efficacy and higher QoL to dogs with otitis externa and their owners, compared to an owner-administered topical otic therapy.

摘要

背景

使用主人自行给药的产品治疗犬外耳炎可能具有挑战性。

目的

评估兽医进行的耳部治疗对患有外耳炎的犬及其主人生活质量(QoL)的影响,以及对耳炎临床和细胞学参数的影响;并与主人自行给药治疗进行比较。

动物

50只客户拥有的犬被随机分为两组,治疗2周。

方法

兽医每隔1周对A组犬使用兽用许可的耳用凝胶进行两次治疗;主人每天对B组犬使用兽用许可的耳滴剂产品进行一次治疗,并每周进行两次清洁。兽医在第0、7、14和28天使用OTI-3量表和半定量细胞学检查评估耳炎情况。每次就诊时,主人使用经过验证的问卷评估生活质量,并使用视觉模拟量表评估瘙痒情况。对每组治疗前后的分数以及组间差异进行统计学分析。

结果

两组中所有参数均有显著改善。在所有时间点,A组犬及其主人的生活质量得分改善均显著高于B组(P < 0.05),第28天主人的生活质量除外。在任何时间点,两组之间OTI-3的改善情况均无差异,而到第7天时,A组的细胞学得分和瘙痒改善更为显著(分别为P = 0.0026和P = 0.0294)。

结论

与主人自行给药的局部耳部治疗相比,兽医给药的耳用凝胶对外耳炎犬及其主人具有同等疗效且生活质量更高。

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