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关联双臂收缩压与心血管疾病风险因素之间的关系。

Correlating the relationship between interarm systolic blood pressure and cardiovascular disease risk factors.

作者信息

Ma Wei, Zhang Baowei, Yang Ying, Qi Litong, Meng Lei, Zhang Yan, Huo Yong

机构信息

Department of Cardiovascular Disease, Peking University First Hospital, Beijing, Beijing, China.

出版信息

J Clin Hypertens (Greenwich). 2017 May;19(5):466-471. doi: 10.1111/jch.12987. Epub 2017 Mar 14.

Abstract

Interarm systolic blood pressure difference (IASBPD) can predict cardiovascular disease. To investigate the relationship between IASBPD and cardiovascular disease risk factors, a total of 1426 individuals were studied. Blood pressure was assessed simultaneously and IASBPD was expressed as the absolute difference value (|R-L|). Cardiovascular disease risk factors were compared between the high IASBPD group (IASBPD ≥10 mm Hg) and the normal IASBPD group (IASBPD <10 mm Hg). An increased prevalence of hypertension, body mass index, and systolic and diastolic blood pressure were observed in the high IASBPD group (P<.05), associated with the enhanced mean values of intima-media thickness and maximum intima-media thickness (P<.05). Brachial-ankle pulse wave velocity was increased, while ankle-brachial index was lower in the high IASBPD group (P<.05). Multivariate logistic regression analysis revealed that IASBPD ≥10 mm Hg was positively associated with body mass index (odds ratio, 1.077; P=.002) and systolic blood pressure (odds ratio, 1.032; P<.001), and negatively associated with ankle-brachial index (odds ratio, 0.038; P<.001).

摘要

双臂收缩压差值(IASBPD)可预测心血管疾病。为研究IASBPD与心血管疾病危险因素之间的关系,共对1426名个体进行了研究。同时评估血压,IASBPD表示为绝对差值(|右-左|)。比较了高IASBPD组(IASBPD≥10 mmHg)和正常IASBPD组(IASBPD<10 mmHg)之间的心血管疾病危险因素。高IASBPD组中高血压、体重指数以及收缩压和舒张压的患病率增加(P<0.05),这与内膜中层厚度平均值和最大内膜中层厚度的增加相关(P<0.05)。高IASBPD组的肱踝脉搏波速度增加,而踝臂指数较低(P<0.05)。多因素逻辑回归分析显示,IASBPD≥10 mmHg与体重指数呈正相关(比值比,1.077;P=0.002)和收缩压呈正相关(比值比,1.032;P<0.001),与踝臂指数呈负相关(比值比,0.038;P<0.001)。

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