Ma Wei, Zhang Baowei, Yang Ying, Qi Litong, Meng Lei, Zhang Yan, Huo Yong
Department of Cardiovascular Disease, Peking University First Hospital, Beijing, Beijing, China.
J Clin Hypertens (Greenwich). 2017 May;19(5):466-471. doi: 10.1111/jch.12987. Epub 2017 Mar 14.
Interarm systolic blood pressure difference (IASBPD) can predict cardiovascular disease. To investigate the relationship between IASBPD and cardiovascular disease risk factors, a total of 1426 individuals were studied. Blood pressure was assessed simultaneously and IASBPD was expressed as the absolute difference value (|R-L|). Cardiovascular disease risk factors were compared between the high IASBPD group (IASBPD ≥10 mm Hg) and the normal IASBPD group (IASBPD <10 mm Hg). An increased prevalence of hypertension, body mass index, and systolic and diastolic blood pressure were observed in the high IASBPD group (P<.05), associated with the enhanced mean values of intima-media thickness and maximum intima-media thickness (P<.05). Brachial-ankle pulse wave velocity was increased, while ankle-brachial index was lower in the high IASBPD group (P<.05). Multivariate logistic regression analysis revealed that IASBPD ≥10 mm Hg was positively associated with body mass index (odds ratio, 1.077; P=.002) and systolic blood pressure (odds ratio, 1.032; P<.001), and negatively associated with ankle-brachial index (odds ratio, 0.038; P<.001).
双臂收缩压差值(IASBPD)可预测心血管疾病。为研究IASBPD与心血管疾病危险因素之间的关系,共对1426名个体进行了研究。同时评估血压,IASBPD表示为绝对差值(|右-左|)。比较了高IASBPD组(IASBPD≥10 mmHg)和正常IASBPD组(IASBPD<10 mmHg)之间的心血管疾病危险因素。高IASBPD组中高血压、体重指数以及收缩压和舒张压的患病率增加(P<0.05),这与内膜中层厚度平均值和最大内膜中层厚度的增加相关(P<0.05)。高IASBPD组的肱踝脉搏波速度增加,而踝臂指数较低(P<0.05)。多因素逻辑回归分析显示,IASBPD≥10 mmHg与体重指数呈正相关(比值比,1.077;P=0.002)和收缩压呈正相关(比值比,1.032;P<0.001),与踝臂指数呈负相关(比值比,0.038;P<0.001)。