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中心旁急性黄斑病变作为白内障超声乳化手术后严重视力丧失患者的一种表现。

Paracentral acute middle maculopathy as a finding in patients with severe vision loss following phacoemulsification cataract surgery.

作者信息

Creese Katarina, Ong Daini, Sandhu Sukhpal S, Ware David, Alex Harper C, Al-Qureshi Salmaan H, Wickremasinghe Sanjeewa S

机构信息

Medical Retina Unit, The Royal Victorian Eye and Ear Hospital, Melbourne, Victoria, Australia.

Centre for Eye Research Australia, University of Melbourne, Melbourne, Victoria, Australia.

出版信息

Clin Exp Ophthalmol. 2017 Aug;45(6):598-605. doi: 10.1111/ceo.12945. Epub 2017 Apr 25.

Abstract

IMPORTANCE

Paracentral acute middle maculopathy (PAMM) diagnosed by spectral domain optical coherence tomography (SD-OCT) in patients with poor visual outcome post cataract surgery.

BACKGROUND

Case series of severe vision loss due to PAMM after cataract surgery.

DESIGN

Retrospective case series.

PARTICIPANTS

Cases from five surgical centres in Victoria, Australia.

METHODS

Retrospective analysis of cases with unexplained 'patch-off' vision loss post cataract surgery. All patients in our cohort had PAMM and presumed diagnosis of central or transient retinal artery occlusion.

MAIN OUTCOME MEASURES

A review of the patient histories focusing on pre-operative ocular and systemic vascular risk factors, anaesthetic and operative factors.

RESULTS

Ten cases were included. All patients had 6/72 Snellen visual acuity or worse noted on day one post surgery. Three patients had features of central retinal artery occlusion consisting of retinal pallor with a 'cherry red' macula but absent relative afferent pupillary defect. Seven had no features of retinal pallor or attenuation of retinal arterioles. On SD-OCT, all eyes had evident PAMM. Six patients had a history of cardiovascular disease or blood dyscrasia.

CONCLUSIONS AND RELEVANCE

PAMM should be considered in patients with 'patch off' visual loss and absence of other fundal signs. We hypothesise that spasm or transient occlusion of central retinal artery leads to arterial hypoperfusion with subsequent ischaemia or infarction of the retina. Underlying arterial disease may have led to pre-existing hypoperfusion that may have been further compromised by raised intraocular pressure during the procedure itself or via raised orbital pressure from the anaesthesia.

摘要

重要性

在白内障手术后视力预后较差的患者中,通过光谱域光学相干断层扫描(SD-OCT)诊断出的黄斑中心凹旁急性黄斑病变(PAMM)。

背景

白内障手术后因PAMM导致严重视力丧失的病例系列。

设计

回顾性病例系列。

参与者

来自澳大利亚维多利亚州五个手术中心的病例。

方法

对白内障手术后原因不明的“片状”视力丧失病例进行回顾性分析。我们队列中的所有患者均患有PAMM,并推测诊断为中央或短暂性视网膜动脉阻塞。

主要观察指标

回顾患者病史,重点关注术前眼部和全身血管危险因素、麻醉和手术因素。

结果

纳入10例病例。所有患者在术后第一天的视力均为6/72 Snellen或更差。3例患者具有视网膜中央动脉阻塞的特征,包括视网膜苍白伴黄斑“樱桃红”,但相对传入瞳孔缺陷阴性。7例患者没有视网膜苍白或视网膜小动脉变细的特征。在SD-OCT上,所有眼睛均有明显的PAMM。6例患者有心血管疾病或血液系统疾病史。

结论及相关性

对于出现“片状”视力丧失且无其他眼底体征的患者,应考虑PAMM。我们推测视网膜中央动脉痉挛或短暂阻塞会导致动脉灌注不足,随后视网膜缺血或梗死。潜在的动脉疾病可能导致先前存在的灌注不足,在手术过程中眼内压升高或麻醉引起的眶压升高可能会进一步加重这种情况。

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