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医院手术量对接受颈动脉支架置入术患者长期神经学预后的影响。

Impact of hospital volume on long-term neurological outcome in patients undergoing carotid artery stenting.

作者信息

Hung Chi-Sheng, Yeh Chih-Fan, Lin Mao-Shin, Chen Ying-Hsien, Huang Ching-Chang, Li Hung-Yuan, Kao Hsien-Li

机构信息

Department of Internal Medicine, National Taiwan University Hospital, Taipei, Taiwan.

出版信息

Catheter Cardiovasc Interv. 2017 Jun 1;89(7):1242-1249. doi: 10.1002/ccd.26989. Epub 2017 Mar 15.

DOI:10.1002/ccd.26989
PMID:28296028
Abstract

BACKGROUND

The impact of hospital volume on long-term outcome after carotid artery stenting (CAS) remains unknown.

OBJECTIVES

We designed a nationwide cohort study to elucidate the impact of hospital volume on the incidence of stroke after CAS.

METHODS

The Taiwan National Health Insurance Research database was used to identify all patients admitted for CAS from 2008 to 2012. We defined high-volume hospitals as those performing more than 20 CAS per year. The primary outcome was new ischemic stroke after discharging from the index CAS. Propensity score-matching was performed to create two matched groups for comparison.

RESULTS

A total of 3,248 patients underwent 3,576 CAS procedures were enrolled. There were 56 hospitals performing CAS during the study period. Among these 3,248 patients, 2,226 (68.5%) were performed in high-volume hospitals. A propensity score-matching created two groups with 1,000 patients in each group. During a median of 2.06 years follow-up, 35 (3.5%) and 52 (5.2%) patients in high-volume hospitals and low-volume hospitals developed new ischemic stroke 30 days after discharging from the index CAS, respectively (for low-volume hospitals, HR 1.50, 95%CI 1.06-2.12, P = 0.023). The use of embolic protection device did not result in different periprocedural or postdischarge strokes. The periprocedural (within 30 days after CAS) ischemic stroke or all-cause mortality rates during follow-up period were similar between two groups.

CONCLUSIONS

CAS performed in high-volume hospitals was associated with less new ischemic stroke after discharging from the index CAS, compared to those in low-volume hospitals. © 2017 Wiley Periodicals, Inc.

摘要

背景

医院手术量对颈动脉支架置入术(CAS)后长期预后的影响尚不清楚。

目的

我们设计了一项全国性队列研究,以阐明医院手术量对CAS后卒中发生率的影响。

方法

利用台湾国民健康保险研究数据库识别出2008年至2012年期间所有因CAS入院的患者。我们将每年进行超过20例CAS手术的医院定义为高手术量医院。主要结局是首次CAS出院后新发缺血性卒中。进行倾向评分匹配以创建两个匹配组进行比较。

结果

共有3248例患者接受了3576例CAS手术。研究期间有56家医院进行CAS手术。在这3248例患者中,2226例(68.5%)在高手术量医院进行手术。倾向评分匹配产生了两组,每组1000例患者。在中位2.06年的随访期间,高手术量医院和低手术量医院分别有35例(3.5%)和52例(5.2%)患者在首次CAS出院后30天发生新发缺血性卒中(低手术量医院,HR 1.50,95%CI 1.06 - 2.12,P = 0.023)。使用栓子保护装置并未导致围手术期或出院后卒中的差异。两组随访期间围手术期(CAS后30天内)缺血性卒中或全因死亡率相似。

结论

与低手术量医院相比,高手术量医院进行的CAS与首次CAS出院后较少的新发缺血性卒中相关。© 2017威利期刊公司。

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