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脊柱手术后细菌性脑膜炎的外科治疗:一例报告

Surgical treatment for bacterial meningitis after spinal surgery: A case report.

作者信息

Zhang Li-Min, Ren Liang, Zhao Zhen-Qi, Zhao Yan-Rui, Zheng Yin-Feng, Zhou Jun-Lin

机构信息

Department of Orthopedics, Beijing Chao-Yang Hospital, Capital Medical University, Beijing Department of Spinal Surgery, The Third Hospital of Shijiazhuang, Shijiazhuang, People's Republic of China.

出版信息

Medicine (Baltimore). 2017 Mar;96(11):e6099. doi: 10.1097/MD.0000000000006099.

Abstract

RATIONALE

Bacterial meningitis (BM) has been recognized as a rare complication of spinal surgery. However, there are few reports on the management of postoperative BM in patients who have undergone spinal surgery. The initial approach to the treatment of patients suspected with acute BM depends on the stage at which the syndrome is recognized, the speed of the diagnostic evaluation, and the need for antimicrobial and adjunctive therapy.

PATIENT CONCERNS

Here, we report the case of a patient with lumbar spinal stenosis and underwent a transforaminal lumbar interbody fusion at L4-L5. The dura mater was damaged intraoperatively. After the surgery, the patient displayed dizziness and vomiting. A CSF culture revealed Pseudomonas aeruginosa infection.

DIAGNOSES

The patient was diagnosed with postoperative BM.

INTERVENTIONS

Antibiotic was administered intravenously depends on the organism isolated. Nevertheless, the patient's clinical condition continued to deteriorate. The patient underwent 2 open revision surgeries for dural lacerations and cyst debridement repair.

OUTCOMES

The patient's mental status returned to normal and her headaches diminished. The patient did not have fever and the infection healed.

LESSONS

Surgical intervention is an effective method to treat BM after spinal operation in cases where conservative treatments have failed. Further, early surgical repair of dural lacerations and cyst debridement can be a treatment option for selected BM patients with complications including pseudomeningocele, wound infection, or cerebrospinal fluid leakage.

摘要

理论依据

细菌性脑膜炎(BM)已被公认为脊柱手术的一种罕见并发症。然而,关于接受脊柱手术患者术后BM的治疗报道较少。疑似急性BM患者的初始治疗方法取决于该综合征被识别的阶段、诊断评估的速度以及对抗菌和辅助治疗的需求。

患者情况

在此,我们报告一例腰椎管狭窄患者,该患者在L4-L5节段接受了经椎间孔腰椎椎间融合术。术中硬脊膜受损。术后,患者出现头晕和呕吐。脑脊液培养显示铜绿假单胞菌感染。

诊断

该患者被诊断为术后BM。

干预措施

根据分离出的病原体静脉给予抗生素。然而,患者的临床状况持续恶化。患者接受了2次开放性翻修手术,用于硬脊膜撕裂修补和囊肿清创修复。

结果

患者的精神状态恢复正常,头痛减轻。患者不再发热,感染愈合。

经验教训

在保守治疗失败的情况下,手术干预是治疗脊柱手术后BM的有效方法。此外,对于包括假性脑脊膜膨出、伤口感染或脑脊液漏等并发症的特定BM患者,早期手术修复硬脊膜撕裂和囊肿清创可能是一种治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ee1b/5369878/a445af272715/medi-96-e6099-g001.jpg

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