Girard P M, Marche C, Maslo C, Rene E, Leport J, Matheron S, Michon C, Coulaud J P, Saimot A G
Service de Maladies Infectieuses et Tropicales, Hôpital Claude-Bernard, Paris.
Ann Med Interne (Paris). 1987;138(6):411-5.
Digestive manifestations of AIDS were studied retrospectively in 87 patients with respect to clinical, microbiological, endoscopic and histological data. Chronic or intermittent diarrhea was observed in 62 p. 100 of patients and frequently associated with major weight loss. The digestive opportunistic infections were: oesophageal candidiasis (42 p. 100), cryptosporidiosis (24 p. 100), cytomegalovirus infections (22 p. 100), isosporiasis (3.4 p. 100), atypical mycobacteriosis (2.2 p. 100), toxoplasmosis (2.2 p. 100). Thirty non-opportunistic agents were detected in 26 patients. Gastrointestinal Kaposi sarcoma occurred in 18 p. 100 of cases. The etiology of diarrhea remained unknown in 16 p. 100 of patients. The value of endoscopy is discussed: esophagogastroduodenal fibroscopy, is usually required to assess oesophageal candidiasis, colonoscopy is required to assess cytomegalovirus colitis on histological data.
我们对87例艾滋病患者的消化系统表现进行了回顾性研究，分析了其临床、微生物学、内镜及组织学数据。62%的患者出现慢性或间歇性腹泻，且常伴有显著体重减轻。消化系统机会性感染包括：食管念珠菌病（42%）、隐孢子虫病（24%）、巨细胞病毒感染（22%）、等孢子球虫病（3.4%）、非典型分枝杆菌病（2.2%）、弓形虫病（2.2%）。26例患者检测出30种非机会性病原体。18%的病例发生胃肠道卡波西肉瘤。16%的患者腹泻病因不明。文中讨论了内镜检查的价值：评估食管念珠菌病通常需要进行食管胃十二指肠纤维镜检查，根据组织学数据评估巨细胞病毒性结肠炎则需要进行结肠镜检查。
