Selik R M, Starcher E T, Curran J W
AIDS Program, Centers for Disease Control, Atlanta, GA 30333.
AIDS. 1987 Sep;1(3):175-82.
To look for associations and trends in the reported frequencies of particular opportunistic diseases in AIDS patients, we analyzed diseases in the 30,632 AIDS patients in the United States reported to the Centers for Disease Control (CDC) by 9 February 1987. Compared with all other AIDS patients, children were three times more likely to have cytomegalovirus disease, homosexual men were seven times more likely to have Kaposi's sarcoma, and Haitian-born patients were six, 14 and 13 times more likely to have toxoplasmosis, tuberculosis, and chronic enteric isosporiasis, respectively. The proportions of patients initially presenting with particular diseases have changed; from before 1983 to 1986, the proportion with Pneumocystis pneumonia climbed from 41.9 to 63.6% and the proportion with extrapulmonary cryptococcosis rose from 4.5 to 6.2%, while Kaposi's sarcoma fell from 30.9 to 14.2%, chronic herpes simplex declined from 4.2 to 2.1%, and toxoplasmosis of the brain dropped from 3.5 to 1.5%.
为了探寻艾滋病患者中特定机会性疾病报告发病率的关联和趋势，我们分析了截至1987年2月9日向美国疾病控制中心（CDC）报告的30632例美国艾滋病患者所患疾病。与所有其他艾滋病患者相比，儿童患巨细胞病毒病的可能性是其三倍，同性恋男性患卡波西肉瘤的可能性是其七倍，出生于海地的患者患弓形虫病、结核病和慢性肠道等孢球虫病的可能性分别是其六倍、十四倍和十三倍。最初表现为特定疾病的患者比例发生了变化；从1983年以前到1986年，患肺孢子菌肺炎的比例从41.9%攀升至63.6%，肺外隐球菌病的比例从4.5%升至6.2%，而卡波西肉瘤的比例从30.9%降至14.2%，慢性单纯疱疹从4.2%降至2.1%，脑弓形虫病从3.5%降至1.5%。
