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[生殖器乳头瘤病毒病变。性伴侣中的共存情况、在宫颈癌中的作用及阴道镜检查的价值]

[Genital papillomavirus lesions. Coexistence in sexual partners, role in cancer of the cervix and value of colposcopy].

作者信息

Gilgenkrantz H

机构信息

Clinique Dermatologique, Hôpital Edouard-Herriot, Lyon.

出版信息

Ann Dermatol Venereol. 1987;114(10):1249-52.

PMID:2829688
Abstract

Since the human papillomavirus is transmissible sexually, an ever increasing number of male patients is seen in dermatology departments. It therefore seems to be important to evaluate the frequency of HPV-related genital lesions in both males and females. Several recent studies have made it clear that concomitant lesions are very often observed in sexual partners. We have tried here to summarize the different data reported in the literature concerning the frequency of HPV lesions and their probable role in cervical cancer. Some human papillomaviruses (types 6 and 11) produce benign lesions while others possess an oncogenic potential (types 16 and 18). Thus, men with venereal condylomas may constitute a group at risk of cervical neoplasia for their female partners. Some authors even consider cancer of the cervix as a sexually transmitted disease. It now becomes necessary to undertake systematic examination of male partners in order to detect viral lesions invisible to the naked eye, particularly before and after acetic acid application on the penis and by means of a colposcope. However, for several reasons given in the conclusion, such an epidemiological study remains difficult to perform.

摘要

由于人乳头瘤病毒具有性传播性,皮肤科门诊中男性患者的数量日益增多。因此,评估男性和女性中与HPV相关的生殖器病变的发生率似乎很重要。最近的几项研究表明,性伴侣中常常会出现伴随病变。我们在此试图总结文献中报道的关于HPV病变发生率及其在宫颈癌中可能作用的不同数据。一些人乳头瘤病毒(6型和11型)会产生良性病变,而其他一些则具有致癌潜力(16型和18型)。因此,患有性病湿疣的男性可能会使其女性伴侣面临宫颈肿瘤形成的风险。一些作者甚至将宫颈癌视为一种性传播疾病。现在有必要对男性伴侣进行系统检查,以便检测肉眼不可见的病毒病变,特别是在阴茎涂抹醋酸前后以及通过阴道镜进行检查时。然而,由于结论中给出的几个原因,这样的流行病学研究仍然难以开展。

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