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慢性腰椎神经根病患者中,透视引导下经椎间孔硬膜外注射类固醇和局部麻醉药与保守治疗的比较

Comparison of fluoroscopic Guided Transforaminal Epidural Injections of Steroid and Local Anaesthetic with Conservative Management in Patients with Chronic Lumbar Radiculopathies.

作者信息

Mehta Nandita, Salaria Misbah, Salaria A Q

机构信息

Department of Anaesthesiology and Pain Management, Acharya Shri Chander College of Medical Sciences and Hospital, Jammu, Jammu and Kashmir, India.

Department of Orthopaedics, Acharya Shri Chander College of Medical Sciences and Hospital, Jammu, Jammu and Kashmir, India.

出版信息

Anesth Essays Res. 2017 Jan-Mar;11(1):17-22. doi: 10.4103/0259-1162.186868.

Abstract

BACKGROUND

Chronic lumbar radiculopathy is a common medical problem and the treatment modalities used over years have been many ranging from conservative or symptomatic management to open decompression surgery. This study was aimed at to compare two modalities of treatment, i.e., conservative and lumbar transforaminal epidural steroid injections (TFESIs).

MATERIALS AND METHODS

A total of 120 patients of American Society of Anesthesiology class - (a healthy patient or a patient with mild systemic disease) were randomized to two groups. Group C ( = 60) were managed conservatively with bed rest, analgesics, and physiotherapy. Group T ( = 60) received lumbar TFESIs with methylprednisolone 40 mg with 2 ml bupivacaine (0.5%). Measurements using visual analog scale (VAS) were taken before treatment and at various time intervals after the start of treatment.

RESULTS

There was no statistically significant difference regarding the demographic characteristics of both groups. The VAS scores were less and statistically significant in Group T after 30 min postinjection, at the 2 week and after 1 month. Recovery rate of straight leg raise test was found to be 98% in those treated with TFESI. The Group T had significantly better patient satisfaction score and additionally there was drug dose intake reduction before and after the treatment.

CONCLUSION

Patients treated with fluoroscopic-guided TFESI have better pain relief, quality-of-life, and less analgesic requirement than those managed conservatively.

摘要

背景

慢性腰椎神经根病是一个常见的医学问题,多年来使用的治疗方式多种多样,从保守或对症治疗到开放减压手术。本研究旨在比较两种治疗方式,即保守治疗和腰椎经椎间孔硬膜外类固醇注射(TFESI)。

材料与方法

总共120例美国麻醉医师协会分级为(健康患者或轻度全身性疾病患者)的患者被随机分为两组。C组(n = 60)采用卧床休息、镇痛药物和物理治疗进行保守治疗。T组(n = 60)接受含40 mg甲泼尼龙和2 ml布比卡因(0.5%)的腰椎TFESI治疗。在治疗前以及治疗开始后的不同时间间隔,使用视觉模拟量表(VAS)进行测量。

结果

两组的人口统计学特征无统计学显著差异。注射后30分钟、2周及1个月后,T组的VAS评分更低且具有统计学显著性。经TFESI治疗的患者直腿抬高试验的恢复率为98%。T组患者满意度评分显著更高,并且治疗前后的药物剂量摄入减少。

结论

与保守治疗的患者相比,接受透视引导下TFESI治疗的患者疼痛缓解更好、生活质量更高且镇痛需求更少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3f89/5341643/a7a0274c065c/AER-11-17-g001.jpg

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