Messeha Medhat Mikhail
Department of Anaesthesia and Surgical Intensive Care, Faculty of Medicine, Mansoura University Hospital, Mansoura, Egypt.
Anesth Essays Res. 2017 Jan-Mar;11(1):88-93. doi: 10.4103/0259-1162.186594.
The ideal intraoperative ventilation strategy in obese patients remains obscure. This prospective, randomized study was designed to evaluate the effect of pressure-controlled ventilation (PCV) before or after volume-controlled ventilation (VCV) on lung mechanics and hemodynamics variables in obese patients subjected to abdominoplasty operation.
The study included forty patients with body mass index 30-45 kg/m subjected to abdominoplasty. All patients were randomly allocated in two groups after the induction of general anesthesia (twenty patients each), according to intraoperative ventilatory strategy. Group I (P-V): started with PCV until the plication of rectus muscle changes into VCV till the end of surgery. Group II (V-P): started with VCV until the plication of rectus muscle changes into PCV till the end of surgery. Lung mechanics, hemodynamics variables (heart rate and mean blood pressure), and arterial blood gases (ABGs) were recorded.
No significant difference in the hemodynamics and ABGs were recorded between the studied groups. The use of PCV after VCV induced the improvement of lung mechanics.
Switching from VCV to PCV is preferred to improve intraoperative oxygenation and lung compliance without adverse hemodynamic effects in obese patients.
肥胖患者理想的术中通气策略仍不明确。本前瞻性随机研究旨在评估在接受腹部整形手术的肥胖患者中,容量控制通气(VCV)之前或之后采用压力控制通气(PCV)对肺力学和血流动力学变量的影响。
该研究纳入了40例体重指数为30 - 45kg/m²且接受腹部整形手术的患者。全身麻醉诱导后,根据术中通气策略将所有患者随机分为两组(每组20例)。第一组(P - V):开始采用PCV,直到腹直肌折叠时改为VCV直至手术结束。第二组(V - P):开始采用VCV,直到腹直肌折叠时改为PCV直至手术结束。记录肺力学、血流动力学变量(心率和平均血压)以及动脉血气(ABG)。
研究组之间在血流动力学和ABG方面未记录到显著差异。VCV后使用PCV可改善肺力学。
在肥胖患者中,从VCV转换为PCV更有利于改善术中氧合和肺顺应性,且无不良血流动力学影响。