El-Sayed Amir Abouzkry, Arafa Sherif Kamal, El-Demerdash Ayman Mohamady
Department of Anaesthesia and Intensive Care, Faculty of Medicine, Aswan University, Aswan, Egypt.
J Anaesthesiol Clin Pharmacol. 2019 Oct-Dec;35(4):468-474. doi: 10.4103/joacp.JOACP_288_18.
Prone positioning may induce alterations of hemodynamic and airway pressure parameters that may affect intraoperative (IO) blood loss. Pressure-controlled ventilation (PCV) may modify these alterations. To observe the relation between ventilation mode and hemodynamic, airway pressure changes, and blood loss during lumbar discectomy performed in the prone position.
Volume-controlled ventilation (VCV) patients were using tidal volume (TV) of 8-10 ml/Kg, but for pressure-controlled ventilation (PCV) patients peak inspiratory pressure (PIP) was adjusted to provide the same TV according to ideal body weight. Respiratory and hemodynamic parameters were recorded in supine (T1), on turning to prone (T2), and on returning to the supine position (T3). Primary outcome included amount of IO blood loss; Secondary outcome included need for blood transfusion, IO hemodynamics, and airway pressure changes.
IO blood loss and central venous pressure (CVP) were significantly higher with VCV than PCV patients. Heart rate and blood pressure were significantly reduced in the prone position with little impact of ventilation mode. Prone positioning resulted in significant increase of P-peak and non-significant decrease of P-mean pressure with VCV, while with PCV resulted in a significantly increased airway pressures. P-peak pressure was significantly lower with PCV in supine and prone positions than VCV. P-mean pressure was significantly lower in supine but significantly higher in the prone position with PCV than VCV.
Prone positioning and VCV were associated with increased CVP and IO blood loss, while PCV could lessen these effects and significantly improve airway pressures.
俯卧位可能会引起血流动力学和气道压力参数的改变,进而可能影响术中失血。压力控制通气(PCV)可能会改变这些变化。观察在俯卧位行腰椎间盘切除术时通气模式与血流动力学、气道压力变化及失血之间的关系。
容量控制通气(VCV)患者的潮气量(TV)为8 - 10 ml/kg,但对于压力控制通气(PCV)患者,根据理想体重调整吸气峰压(PIP)以提供相同的潮气量。在仰卧位(T1)、转为俯卧位时(T2)和恢复仰卧位时(T3)记录呼吸和血流动力学参数。主要结局包括术中失血量;次要结局包括输血需求、术中血流动力学和气道压力变化。
VCV患者的术中失血量和中心静脉压(CVP)显著高于PCV患者。俯卧位时心率和血压显著降低,通气模式影响较小。VCV时,俯卧位导致P峰显著升高和P平均压无显著降低,而PCV则导致气道压力显著升高。仰卧位和俯卧位时,PCV的P峰压均显著低于VCV。PCV时,仰卧位P平均压显著低于VCV,但俯卧位时显著高于VCV。
俯卧位和VCV与CVP升高和术中失血增加有关,而PCV可减轻这些影响并显著改善气道压力。