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《奥尔德姆笔记:1969 - 1978年体外受精发展分析。第五章。重新评估琼·珀迪的角色》

The Oldham Notebooks: an analysis of the development of IVF 1969-1978. V. The role of Jean Purdy reassessed.

作者信息

Johnson Martin H, Elder Kay

机构信息

Anatomy School and Centre for Trophoblast Research, Department of Physiology, Development and Neuroscience, Downing Street, Cambridge CB2 3DY, UK.

Bourn Hall Clinic, Bourn, Cambridge CB23 2TN.

出版信息

Reprod Biomed Soc Online. 2015 Jun;1(1):46-57. doi: 10.1016/j.rbms.2015.04.005.

Abstract

The role of Jean Purdy in the work leading to the birth of Louise Brown is assessed. We report that Purdy: (i) recorded and organized most of the data systematically; (ii) probably spent longer working in Oldham than did Edwards; (iii) whilst there, was primarily responsible for organizing laboratory supplies, including media preparation and testing; (iv) was involved in patient care; and (v) was a major source of support to Edwards. We find that Purdy, despite her nursing qualification, was not involved in laparoscopic egg retrieval and clinical aspects, but was focused on basic research activities. The evidence on who was present at embryo transfers is less clear, but suggests that Edwards was present for all, whereas Purdy may have been absent for some. Overall, we conclude that Purdy's role was a highly significant and under-appreciated element in the achievement of IVF in Oldham.

摘要

本文评估了琼·珀迪在导致路易丝·布朗诞生的工作中所扮演的角色。我们报告称,珀迪:(i)系统地记录并整理了大部分数据;(ii)在奥尔德姆工作的时间可能比爱德华兹更长;(iii)在那里时,主要负责组织实验室用品,包括培养基的制备和测试;(iv)参与了患者护理;以及(v)是爱德华兹的主要支持来源。我们发现,尽管珀迪拥有护理资质,但她并未参与腹腔镜取卵及临床相关工作,而是专注于基础研究活动。关于胚胎移植时谁在场的证据不太明确,但表明爱德华兹每次都在场,而珀迪可能有几次不在场。总体而言,我们得出结论,珀迪的角色是奥尔德姆试管婴儿成功过程中一个极其重要且未得到充分认可的因素。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7684/6124348/61d4e51b4e86/gr1.jpg

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