Balakrishnan Revathi, Nguyen Brian, Raad Roy, Donnino Robert, Naidich David P, Jacobs Jill E, Reynolds Harmony R
Cardiovascular Clinical Research Center, Leon H. Charney Division of Cardiology, New York University School of Medicine, New York, New York.
Department of Radiology, New York University School of Medicine, New York, New York.
Clin Cardiol. 2017 Jul;40(7):498-502. doi: 10.1002/clc.22685. Epub 2017 Mar 16.
Coronary artery calcification as assessed by computed tomography (CT) is a validated predictor of cardiovascular risk, whether identified on a dedicated cardiac study or on a routine non-gated chest CT. The prevalence of incidentally detected coronary artery calcification on non-gated chest CT imaging and consistency of reporting have not been well characterized.
Coronary calcification is present on chest CT in some patients not taking statin therapy and may be under-reported.
Non-gated chest CT images dated 1/1/2012 to 1/1/2013 were retrospectively reviewed. Demographics and medical history were obtained from charts. Patients with known history of coronary revascularization and/or pacemaker/defibrillator were excluded. Two independent readers with cardiac CT expertise evaluated images for the presence and anatomical distribution of any coronary calcification, blinded to all clinical information including CT reports. Original clinical CT reports were subsequently reviewed.
Coronary calcification was identified in 204/304 (68%) chest CTs. Patients with calcification were older and had more hyperlipidemia, smoking history, and known coronary artery disease. Of patients with calcification, 43% were on aspirin and 62% were on statin medication at the time of CT. Coronary calcification was identified in 69% of reports when present.
A high prevalence of coronary calcification was found in non-gated chest CT scans performed for non-cardiac indications. In one-third, coronary calcification was not mentioned in the clinical report when actually present. In this population of patients with cardiac risk factors, standard reporting of the presence of coronary calcification may provide an opportunity for risk factor modification.
通过计算机断层扫描(CT)评估的冠状动脉钙化是心血管风险的有效预测指标,无论是在专门的心脏检查中还是在常规非门控胸部CT上发现。非门控胸部CT成像上偶然发现的冠状动脉钙化的患病率及报告的一致性尚未得到充分描述。
在一些未接受他汀类药物治疗的患者中,胸部CT上存在冠状动脉钙化,且可能报告不足。
回顾性分析2012年1月1日至2013年1月1日的非门控胸部CT图像。从病历中获取人口统计学和病史信息。排除有冠状动脉血运重建和/或起搏器/除颤器已知病史的患者。两名具有心脏CT专业知识的独立阅片者在不知道包括CT报告在内的所有临床信息的情况下,评估图像中是否存在任何冠状动脉钙化及其解剖分布。随后查阅原始临床CT报告。
在304例胸部CT中,204例(68%)发现冠状动脉钙化。有钙化的患者年龄较大,高脂血症、吸烟史和已知冠状动脉疾病的发生率更高。在有钙化的患者中,43%在CT检查时服用阿司匹林,62%服用他汀类药物。当存在冠状动脉钙化时,69%的报告中提到了这一情况。
在因非心脏指征进行的非门控胸部CT扫描中,冠状动脉钙化的患病率很高。在三分之一的病例中,临床报告中实际存在冠状动脉钙化时却未提及。在这群有心脏危险因素的患者中,对冠状动脉钙化的存在进行标准报告可能为调整危险因素提供机会。