转录延伸。
Transcription elongation.
作者信息
Mustaev Arkady, Roberts Jeffrey, Gottesman Max
机构信息
a PHRI Center, NJMS, Rutgers, The State University of New Jersey , Newark , NJ , USA.
b Department of Molecular Biology and Genetics , Cornell University , Ithaca , NY , USA.
出版信息
Transcription. 2017 May 27;8(3):150-161. doi: 10.1080/21541264.2017.1289294. Epub 2017 Feb 8.
Abstract
This review is focused on recent progress in understanding how Escherichia coli RNAP polymerase translocates along the DNA template and the factors that affect this movement. We discuss the fundamental aspects of RNAP translocation, template signals that influence forward or backward movement, and host or phage factors that modulate translocation.
摘要
本综述聚焦于在理解大肠杆菌RNA聚合酶如何沿DNA模板移位以及影响该移位的因素方面的最新进展。我们讨论了RNA聚合酶移位的基本方面、影响向前或向后移动的模板信号，以及调节移位的宿主或噬菌体因素。
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本文引用的文献
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Structural insights into NusG regulating transcription elongation.NusG调控转录延伸的结构见解。
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NusG inhibits RNA polymerase backtracking by stabilizing the minimal transcription bubble.NusG通过稳定最小转录泡来抑制RNA聚合酶回溯。
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Molecular Basis of NusG-mediated Regulation of Rho-dependent Transcription Termination in Bacteria.细菌中NusG介导的Rho依赖性转录终止调控的分子基础
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Reconstruction of bacterial transcription-coupled repair at single-molecule resolution.在单分子分辨率下重建细菌转录偶联修复。
Nature. 2016 Aug 11;536(7615):234-7. doi: 10.1038/nature19080. Epub 2016 Aug 3.
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Probing the structure of Nun transcription arrest factor bound to RNA polymerase.探究与RNA聚合酶结合的Nun转录终止因子的结构。
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Science. 2016 May 20;352(6288):993-6. doi: 10.1126/science.aad6945.
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