Pinto L F, Marín-Montesinos I, Lloveras V, Muñoz-Gómez J L, Pons M, Veciana J, Vidal-Gancedo J
Institut de Ciència de Materials de Barcelona (ICMAB-CSIC), Bellaterra, Spain.
Biomolecular NMR laboratory, Inorganic and Organic Chemistry Department, University of Barcelona, Baldiri Reixac 10-12, 08028, Barcelona, Spain.
Chem Commun (Camb). 2017 Mar 28;53(26):3757-3760. doi: 10.1039/c7cc00635g.
Herein, we report the synthesis and the study of a novel mixed biradical with BDPA and TEMPO radical units that are covalently bound by an ester group (BDPAesterTEMPO) as a polarizing agent for fast dissolution DNP. The biradical exhibits an extremely high DNP NMR enhancement of >50 000 times, which constitutes one of the largest signal enhancements observed so far, to the best of our knowledge.
在此，我们报告了一种新型混合双自由基的合成与研究，该双自由基由BDPA和TEMPO自由基单元通过酯基共价连接而成（BDPAesterTEMPO），作为用于快速溶解动态核极化（DNP）的极化剂。据我们所知，该双自由基表现出极高的DNP核磁共振增强，超过50000倍，这是迄今为止观察到的最大信号增强之一。
