a Faculty of Chemistry, Department of Analytical Chemistry , Gdańsk University of Technology , Gdańsk , Poland.
b Faculty of Chemistry, Department of Chemical and Process Engineering , Gdańsk University of Technology , Gdańsk , Poland.
Crit Rev Anal Chem. 2017 Jul 4;47(4):340-358. doi: 10.1080/10408347.2017.1298986. Epub 2017 Mar 17.
One of the major sources of error that occur during chemical analysis utilizing the more conventional and established analytical techniques is the possibility of losing part of the analytes during the sample preparation stage. Unfortunately, this sample preparation stage is required to improve analytical sensitivity and precision. Direct techniques have helped to shorten or even bypass the sample preparation stage; and in this review, we comment of some of the new direct techniques that are mass-spectrometry based. The study presents information about the measurement techniques using mass spectrometry, which allow direct sample analysis, without sample preparation or limiting some pre-concentration steps. MALDI - MS, PTR - MS, SIFT - MS, DESI - MS techniques are discussed. These solutions have numerous applications in different fields of human activity due to their interesting properties. The advantages and disadvantages of these techniques are presented. The trends in development of direct analysis using the aforementioned techniques are also presented.
在利用更传统和成熟的分析技术进行化学分析时，其中一个主要的误差来源是在样品制备阶段可能会丢失部分分析物。不幸的是，这个样品制备阶段是提高分析灵敏度和精度所必需的。直接技术有助于缩短甚至绕过样品制备阶段；在这篇综述中，我们评论了一些基于质谱的新的直接技术。本研究介绍了使用质谱进行测量技术的信息，这些技术允许直接进行样品分析，而无需进行样品制备或限制某些预浓缩步骤。讨论了 MALDI-MS、PTR-MS、SIFT-MS、DESI-MS 技术。由于其有趣的性质，这些解决方案在人类活动的不同领域有许多应用。介绍了这些技术的优缺点。还介绍了使用上述技术进行直接分析的发展趋势。
