Yamamura H
Institut für Humangenetik und vergleichende Erbpathologie der Johann Wolfgang Goethe-Universität Frankfurt a. Main, Deutschland.
Anatomisches Institut der Universität Kyoto, Japan.
Wilhelm Roux Arch Entwickl Mech Org. 1969 Sep;162(3):218-242. doi: 10.1007/BF00576930.
Individual differences in developmental stages of mouse embryos of the two related strains C57 BL/6JHanFfm and C57BL/10JFfm during the period between day VIII and day X p.c. have been examined.The following results were obtained: 1. A remarkable variability in the number of somites could be stated in embryos of different litters but also in embryos of the same litter, especially at stages day IX and day IX +12 h. 2. There was a close relationship between the number of somites and progresses of rotation from the S- to the C-shape. Incidence of pre-rotation stages was higher in embryos of strain C57BL/6 than in embryos of strain C57BL/10. 3. Individual differences were stated in the developmental stages of neural groove and upper limb buds. The degree of differentiation and closure of the neural groove was more progressive in strain C57BL/10. 4. Individual differences were also registered in the appearance and development of the following primordia: eye, ear, heart, thyroid, lung, liver, ureter and the pronephric ducts. 5. The body length of the embryos was closely related to the number of somites.
对两个相关品系C57 BL/6JHanFfm和C57BL/10JFfm的小鼠胚胎在受孕第8天至第10天期间发育阶段的个体差异进行了研究。得到以下结果：1. 不同窝的胚胎以及同一窝的胚胎中，尤其是在第9天和第9天+12小时阶段，体节数量存在显著差异。2. 体节数量与从S形到C形的旋转进程之间存在密切关系。C57BL/6品系胚胎中旋转前期的发生率高于C57BL/10品系胚胎。3. 在神经沟和上肢芽的发育阶段存在个体差异。C57BL/10品系中神经沟的分化和闭合程度更先进。4. 在以下原基的出现和发育中也记录到个体差异：眼睛、耳朵、心脏、甲状腺、肺、肝脏、输尿管和前肾管。5. 胚胎的体长与体节数量密切相关。
